Study of the 'Raman spectroscopic signature of life' in mitochondria isolated from budding yeast

Liang da Chiu, Masahiro Ando, Hiro o. Hamaguchi

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

The 'Raman spectroscopic signature of life' is a Raman band at 1602 cm-1 that sharply reflects the metabolic activity of cell mitochondria. Here we report the study of thissignature in isolated yeast mitochondria. The existence and behaviour of the 1602 cm-1 band in isolated mitochondria have been confirmed to be the same as in living yeast cells: the intensity of the band decreases with timewhen a respiration inhibitor, sodium azide, is added. The present study shows the significance of isolated mitochondria in elucidating the origin of this still unassigned Raman band.

Original languageEnglish
Pages (from-to)2-3
Number of pages2
JournalJournal of Raman Spectroscopy
Volume41
Issue number1
DOIs
Publication statusPublished - 2010 Jan 1
Externally publishedYes

Keywords

  • Budding yeast
  • Metabolic activity
  • Mitochondria
  • Raman spectroscopic signature of life
  • Respiration inhibition

ASJC Scopus subject areas

  • Materials Science(all)
  • Spectroscopy

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