Study on electron microbeam generation for MRT based on photo-cathode rf-gun

Y. Yoshida, Kazuyuki Sakaue, Masakazu Washio

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have been developing an MRT (Microbeam Radition Therapy) based on Cs-Te photo-cathode RF-Gun at Waseda University. MRT is proposed to treat tumors by using array of several micro-meter parallel beams. In this therapy, irradiated normal tissue repairs itself, by contrast, even a non-irradiated tumor tissue dies. In the other words, the microbeam enhances the radiation sensitivity difference between normal and tumor issues. Therefore, MRT is considered one of the most useful tumor therapies in the future. We have generated electron microbeam by tungsten collimator slit and analyzed their dose distribution in air and in the PMMA phantom. We have used radiochromic film called GAFCHROMIC dosimetry film type HD-810 to measure them. We have compared these experimental results with Monte Carlo simulation of the dose distribution using the EGS5 code. In this conference, we would like to report the electron microbeam procedure, optimization of irradiation condition and evaluation of microbeam specifications. Coyright

Original languageEnglish
Title of host publicationIPAC 2012 - International Particle Accelerator Conference 2012
Pages4086-4088
Number of pages3
Publication statusPublished - 2012
Event3rd International Particle Accelerator Conference 2012, IPAC 2012 - New Orleans, LA
Duration: 2012 May 202012 May 25

Other

Other3rd International Particle Accelerator Conference 2012, IPAC 2012
CityNew Orleans, LA
Period12/5/2012/5/25

Fingerprint

microbeams
therapy
cathodes
tumors
electrons
dosage
collimators
dosimeters
slits
specifications
tungsten
optimization
irradiation
evaluation
air
radiation

ASJC Scopus subject areas

  • Nuclear and High Energy Physics

Cite this

Yoshida, Y., Sakaue, K., & Washio, M. (2012). Study on electron microbeam generation for MRT based on photo-cathode rf-gun. In IPAC 2012 - International Particle Accelerator Conference 2012 (pp. 4086-4088)

Study on electron microbeam generation for MRT based on photo-cathode rf-gun. / Yoshida, Y.; Sakaue, Kazuyuki; Washio, Masakazu.

IPAC 2012 - International Particle Accelerator Conference 2012. 2012. p. 4086-4088.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yoshida, Y, Sakaue, K & Washio, M 2012, Study on electron microbeam generation for MRT based on photo-cathode rf-gun. in IPAC 2012 - International Particle Accelerator Conference 2012. pp. 4086-4088, 3rd International Particle Accelerator Conference 2012, IPAC 2012, New Orleans, LA, 12/5/20.
Yoshida Y, Sakaue K, Washio M. Study on electron microbeam generation for MRT based on photo-cathode rf-gun. In IPAC 2012 - International Particle Accelerator Conference 2012. 2012. p. 4086-4088
Yoshida, Y. ; Sakaue, Kazuyuki ; Washio, Masakazu. / Study on electron microbeam generation for MRT based on photo-cathode rf-gun. IPAC 2012 - International Particle Accelerator Conference 2012. 2012. pp. 4086-4088
@inproceedings{36466c1f121c48d3a06c10c608e0e9b4,
title = "Study on electron microbeam generation for MRT based on photo-cathode rf-gun",
abstract = "We have been developing an MRT (Microbeam Radition Therapy) based on Cs-Te photo-cathode RF-Gun at Waseda University. MRT is proposed to treat tumors by using array of several micro-meter parallel beams. In this therapy, irradiated normal tissue repairs itself, by contrast, even a non-irradiated tumor tissue dies. In the other words, the microbeam enhances the radiation sensitivity difference between normal and tumor issues. Therefore, MRT is considered one of the most useful tumor therapies in the future. We have generated electron microbeam by tungsten collimator slit and analyzed their dose distribution in air and in the PMMA phantom. We have used radiochromic film called GAFCHROMIC dosimetry film type HD-810 to measure them. We have compared these experimental results with Monte Carlo simulation of the dose distribution using the EGS5 code. In this conference, we would like to report the electron microbeam procedure, optimization of irradiation condition and evaluation of microbeam specifications. Coyright",
author = "Y. Yoshida and Kazuyuki Sakaue and Masakazu Washio",
year = "2012",
language = "English",
isbn = "9783954501151",
pages = "4086--4088",
booktitle = "IPAC 2012 - International Particle Accelerator Conference 2012",

}

TY - GEN

T1 - Study on electron microbeam generation for MRT based on photo-cathode rf-gun

AU - Yoshida, Y.

AU - Sakaue, Kazuyuki

AU - Washio, Masakazu

PY - 2012

Y1 - 2012

N2 - We have been developing an MRT (Microbeam Radition Therapy) based on Cs-Te photo-cathode RF-Gun at Waseda University. MRT is proposed to treat tumors by using array of several micro-meter parallel beams. In this therapy, irradiated normal tissue repairs itself, by contrast, even a non-irradiated tumor tissue dies. In the other words, the microbeam enhances the radiation sensitivity difference between normal and tumor issues. Therefore, MRT is considered one of the most useful tumor therapies in the future. We have generated electron microbeam by tungsten collimator slit and analyzed their dose distribution in air and in the PMMA phantom. We have used radiochromic film called GAFCHROMIC dosimetry film type HD-810 to measure them. We have compared these experimental results with Monte Carlo simulation of the dose distribution using the EGS5 code. In this conference, we would like to report the electron microbeam procedure, optimization of irradiation condition and evaluation of microbeam specifications. Coyright

AB - We have been developing an MRT (Microbeam Radition Therapy) based on Cs-Te photo-cathode RF-Gun at Waseda University. MRT is proposed to treat tumors by using array of several micro-meter parallel beams. In this therapy, irradiated normal tissue repairs itself, by contrast, even a non-irradiated tumor tissue dies. In the other words, the microbeam enhances the radiation sensitivity difference between normal and tumor issues. Therefore, MRT is considered one of the most useful tumor therapies in the future. We have generated electron microbeam by tungsten collimator slit and analyzed their dose distribution in air and in the PMMA phantom. We have used radiochromic film called GAFCHROMIC dosimetry film type HD-810 to measure them. We have compared these experimental results with Monte Carlo simulation of the dose distribution using the EGS5 code. In this conference, we would like to report the electron microbeam procedure, optimization of irradiation condition and evaluation of microbeam specifications. Coyright

UR - http://www.scopus.com/inward/record.url?scp=84885582878&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84885582878&partnerID=8YFLogxK

M3 - Conference contribution

SN - 9783954501151

SP - 4086

EP - 4088

BT - IPAC 2012 - International Particle Accelerator Conference 2012

ER -