Subsites for substrate recognition by bacterial ribonuclease P.

Akihiro Fujimoto, Satoshi Suwa, Yasuhiro Nagai, Yo Kikuchi, Terumichi Tanaka

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Abstract

We have prepared series of shape variant RNAs of a tRNA precursor and analyzed the substrate shape recognition by bacterial ribonuclease P ribozyme and holoenzyme. The results showed the evidence for the presence of subsites for the recognition of the trna shape. We will discuss a new model for substrate recognition and the role of the protein component.

Original languageEnglish
Pages (from-to)207-208
Number of pages2
JournalNucleic acids symposium series (2004)
Issue number52
Publication statusPublished - 2008
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Fujimoto, A., Suwa, S., Nagai, Y., Kikuchi, Y., & Tanaka, T. (2008). Subsites for substrate recognition by bacterial ribonuclease P. Nucleic acids symposium series (2004), (52), 207-208.