Abstract
We have prepared series of shape variant RNAs of a tRNA precursor and analyzed the substrate shape recognition by bacterial ribonuclease P ribozyme and holoenzyme. The results showed the evidence for the presence of subsites for the recognition of the trna shape. We will discuss a new model for substrate recognition and the role of the protein component.
| Original language | English |
|---|---|
| Pages (from-to) | 207-208 |
| Number of pages | 2 |
| Journal | Nucleic acids symposium series (2004) |
| Issue number | 52 |
| Publication status | Published - 2008 |
| Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)