Subsites for substrate recognition by bacterial ribonuclease P.

Akihiro Fujimoto*, Satoshi Suwa, Yasuhiro Nagai, Yo Kikuchi, Terumichi Tanaka

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


We have prepared series of shape variant RNAs of a tRNA precursor and analyzed the substrate shape recognition by bacterial ribonuclease P ribozyme and holoenzyme. The results showed the evidence for the presence of subsites for the recognition of the trna shape. We will discuss a new model for substrate recognition and the role of the protein component.

Original languageEnglish
Pages (from-to)207-208
Number of pages2
JournalNucleic acids symposium series (2004)
Issue number52
Publication statusPublished - 2008
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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