Super helix formation of actin filaments in an in vitro motile system

Yuichiro Tanaka, Akihiko Ishijima, Shin'ichi Ishiwata

    Research output: Contribution to journalArticle

    27 Citations (Scopus)

    Abstract

    Muscle contraction results from relative sliding of actin and myosin filaments. However, the possibility that actin filaments twist or rotate during sliding has not yet been experimentally investigated. We found that a super helix of an actin filament is formed in an in vitro motile system. This fact suggests that an actin filament twists and rotates due to a torque component of a sliding force generated at cross-bridges.

    Original languageEnglish
    Pages (from-to)94-98
    Number of pages5
    JournalBiochimica et Biophysica Acta (BBA)/Protein Structure and Molecular
    Volume1159
    Issue number1
    DOIs
    Publication statusPublished - 1992 Sep 4

    Fingerprint

    Actin Cytoskeleton
    Actins
    Torque
    Myosins
    Muscle Contraction
    Muscle
    In Vitro Techniques

    Keywords

    • Actin filament
    • Muscle contraction
    • Mutile system
    • Super helix formation

    ASJC Scopus subject areas

    • Biochemistry
    • Biophysics
    • Molecular Biology
    • Structural Biology

    Cite this

    Super helix formation of actin filaments in an in vitro motile system. / Tanaka, Yuichiro; Ishijima, Akihiko; Ishiwata, Shin'ichi.

    In: Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular, Vol. 1159, No. 1, 04.09.1992, p. 94-98.

    Research output: Contribution to journalArticle

    Tanaka, Yuichiro ; Ishijima, Akihiko ; Ishiwata, Shin'ichi. / Super helix formation of actin filaments in an in vitro motile system. In: Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular. 1992 ; Vol. 1159, No. 1. pp. 94-98.
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