Surface hydrophilic treatment of polyurea film realized by vacuum ultraviolet light irradiation and its application for poly(methylmethacrylate) blood analysis chip

H. Shinohara, Y. Takahashi, Jun Mizuno, Shuichi Shoji

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A room temperature hydrophilic method of the polyurea film surface was developed using vacuum ultraviolet (VUV) light at 172 nm in wavelength. The treated film has highly hydrophilic surface for long time (∼2 months). The stable hydrophilic surface, water contact angle of smaller than 20°, was realized. It is kept even after very hard condition of ultrasonic cleaning in de-ionized water. The polyurea film was applied for poly(methylmethacrylate) (PMMA) blood analysis chip. The performance of the surface treatment was evaluated by actual human whole blood flow. The new chip can reduce the adhesion of platelets and white blood cells, even after ultrasonic cleaning in surfactant-induced water.

Original languageEnglish
Pages (from-to)374-379
Number of pages6
JournalSensors and Actuators, B: Chemical
Volume132
Issue number2
DOIs
Publication statusPublished - 2008 Jun 16

Fingerprint

Methylmethacrylate
surface treatment
ultrasonic cleaning
Ultrasonic cleaning
ultraviolet radiation
blood
Surface treatment
Blood
chips
Irradiation
Vacuum
vacuum
irradiation
leukocytes
Water
blood flow
Platelets
platelets
surface water
Surface waters

Keywords

  • Blood analysis chip
  • Hydrophilic treatment
  • Poly(methylmethacrylate)
  • Polyurea film
  • Vacuum ultraviolet light

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry
  • Electrical and Electronic Engineering

Cite this

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AU - Shoji, Shuichi

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AB - A room temperature hydrophilic method of the polyurea film surface was developed using vacuum ultraviolet (VUV) light at 172 nm in wavelength. The treated film has highly hydrophilic surface for long time (∼2 months). The stable hydrophilic surface, water contact angle of smaller than 20°, was realized. It is kept even after very hard condition of ultrasonic cleaning in de-ionized water. The polyurea film was applied for poly(methylmethacrylate) (PMMA) blood analysis chip. The performance of the surface treatment was evaluated by actual human whole blood flow. The new chip can reduce the adhesion of platelets and white blood cells, even after ultrasonic cleaning in surfactant-induced water.

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