Surface modification of PET films using pulsed AC plasma polymerisation aimed at preventing protein adsorption

Zahida Ademovic, Jiang Wei, Bjørn Winther-Jensen, Xiaolin Hou, Peter Kingshott

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

We utilise pulsed AC plasma polymerisation to create thin films that either contain reactive acid functional groups (by deposition of maleic anhydride (MAH) followed by hydrolysis) or are poly (ethylene glycol) (PEG)-like in nature (by using diethylene glycol vinyl ether (DEGVE) as monometer). The MAH films were further modified with PEG chains using a two-step wet chemical method. For the DEGVE films the plasma power was varied in order to change the degree of monomer fragmentation and thus retention of PEG-like character. The chemistry of the surfaces was determined using Fourier-transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), and time-of-flight secondary ion mass spectroscopy (ToF SIMS). Significant reduction (up to 90%) in protein adsorption was achieved by the plasma polymer surfaces as determined using 125I-radiolabelled fibrinogen adsorption experiments.

Original languageEnglish
Pages (from-to)53-63
Number of pages11
JournalPlasma Processes and Polymers
Volume2
Issue number1
DOIs
Publication statusPublished - 2005 Jan 12
Externally publishedYes

Fingerprint

Plasma polymerization
Polyethylene glycols
Surface treatment
glycols
alternating current
polymerization
Maleic Anhydrides
anhydrides
proteins
Proteins
Adsorption
adsorption
ethers
Maleic anhydride
Glycols
fibrinogen
Ethers
Plasmas
hydrolysis
fragmentation

Keywords

  • AC plasma polymerisation
  • Biomaterials
  • Non-fouling coatings
  • Protein adsorption
  • ToF-SIMS
  • XPS

ASJC Scopus subject areas

  • Polymers and Plastics
  • Physics and Astronomy (miscellaneous)

Cite this

Surface modification of PET films using pulsed AC plasma polymerisation aimed at preventing protein adsorption. / Ademovic, Zahida; Wei, Jiang; Winther-Jensen, Bjørn; Hou, Xiaolin; Kingshott, Peter.

In: Plasma Processes and Polymers, Vol. 2, No. 1, 12.01.2005, p. 53-63.

Research output: Contribution to journalArticle

Ademovic, Zahida ; Wei, Jiang ; Winther-Jensen, Bjørn ; Hou, Xiaolin ; Kingshott, Peter. / Surface modification of PET films using pulsed AC plasma polymerisation aimed at preventing protein adsorption. In: Plasma Processes and Polymers. 2005 ; Vol. 2, No. 1. pp. 53-63.
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