Synergism of Ce (IV) and Pr(III) for the fastest non-enzymatic DNA hydrolysis ever.

N. Takeda; M. Irisawa; T. Imai; M. Yashiro; M. Komiyama

Synergism of Ce (IV) and Pr(III) for the fastest non-enzymatic DNA hydrolysis ever.

N. Takeda^*, M. Irisawa, T. Imai, M. Yashiro, M. Komiyama

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

By the synergistic catalysis of Ce4+ and Pr3+, DNA is efficiently hydrolyzed at so far the highest rate. When [Ce4+] = 10 mM and [Pr3+] = 5 mM, the half-life of dinucleotide hydrolysis at pH 7 and 50 degrees C is only 24 min. This catalytic activity is 9 times as large as that of Ce4+, which is the only prominent catalyst hitherto reported. The Ce(4+)-Nd3+ combination is also effective. These bimetallic catalytic systems are eminent tools for the future molecular biology and biotechnology.

Original language	English
Pages (from-to)	207-208
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	34
Publication status	Published - 1995
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Synergism of Ce (IV) and Pr(III) for the fastest non-enzymatic DNA hydrolysis ever.",

abstract = "By the synergistic catalysis of Ce4+ and Pr3+, DNA is efficiently hydrolyzed at so far the highest rate. When [Ce4+] = 10 mM and [Pr3+] = 5 mM, the half-life of dinucleotide hydrolysis at pH 7 and 50 degrees C is only 24 min. This catalytic activity is 9 times as large as that of Ce4+, which is the only prominent catalyst hitherto reported. The Ce(4+)-Nd3+ combination is also effective. These bimetallic catalytic systems are eminent tools for the future molecular biology and biotechnology.",

author = "N. Takeda and M. Irisawa and T. Imai and M. Yashiro and M. Komiyama",

year = "1995",

language = "English",

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journal = "Nucleic acids symposium series",

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T1 - Synergism of Ce (IV) and Pr(III) for the fastest non-enzymatic DNA hydrolysis ever.

AU - Takeda, N.

AU - Irisawa, M.

AU - Imai, T.

AU - Yashiro, M.

AU - Komiyama, M.

PY - 1995

Y1 - 1995

N2 - By the synergistic catalysis of Ce4+ and Pr3+, DNA is efficiently hydrolyzed at so far the highest rate. When [Ce4+] = 10 mM and [Pr3+] = 5 mM, the half-life of dinucleotide hydrolysis at pH 7 and 50 degrees C is only 24 min. This catalytic activity is 9 times as large as that of Ce4+, which is the only prominent catalyst hitherto reported. The Ce(4+)-Nd3+ combination is also effective. These bimetallic catalytic systems are eminent tools for the future molecular biology and biotechnology.

AB - By the synergistic catalysis of Ce4+ and Pr3+, DNA is efficiently hydrolyzed at so far the highest rate. When [Ce4+] = 10 mM and [Pr3+] = 5 mM, the half-life of dinucleotide hydrolysis at pH 7 and 50 degrees C is only 24 min. This catalytic activity is 9 times as large as that of Ce4+, which is the only prominent catalyst hitherto reported. The Ce(4+)-Nd3+ combination is also effective. These bimetallic catalytic systems are eminent tools for the future molecular biology and biotechnology.

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M3 - Article

C2 - 8841625

AN - SCOPUS:0029433598

SN - 0261-3166

SP - 207

EP - 208

JO - Nucleic acids symposium series

JF - Nucleic acids symposium series

IS - 34

ER -

Synergism of Ce (IV) and Pr(III) for the fastest non-enzymatic DNA hydrolysis ever.

Abstract

ASJC Scopus subject areas

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