Synthesis and kinetic cyclisation of quinine-derived oligomers

Stuart J. Rowan, Paul A. Brady, Jeremy K M Sanders

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The synthesis and kinetic cyclisations of a series of linear quinine oligomers are described. The distribution of cyclic oligomers is different from that observed in the corresponding thermodynamic cyclisation: cyclic tetramer is observed in the kinetic cyclisations, indicating that its absence under thermodynamic conditions is not due to any kinetic barrier to its formation.

Original languageEnglish
Pages (from-to)6013-6016
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number33
DOIs
Publication statusPublished - 1996 Aug 12
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

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