Synthesis of β-amino ketones by iridium(III)-catalyzed direct-Mannich reaction

Shunsuke Sueki; Takeyuki Igarashi; Takayuki Nakajima; Isao Shimizu

doi:10.1246/cl.2006.682

Synthesis of β-amino ketones by iridium(III)-catalyzed direct-Mannich reaction

Shunsuke Sueki, Takeyuki Igarashi, Takayuki Nakajima, Isao Shimizu

Waseda University

Research output: Contribution to journal › Article

6 Citations (Scopus)

Abstract

The direct-Mannich reaction of ketones 1, aldehydes 2, and anilines 3 was studied using catalytic amount of transition-metal complexes. The trivalent iridium complex, [IrCl₂(H)(COd)]₂, catalyzed the direct-Mannich reaction effectively to give various β-amino kenotes in good yields under mild conditions.

Original language	English
Pages (from-to)	682-683
Number of pages	2
Journal	Chemistry Letters
Volume	35
Issue number	6
DOIs	https://doi.org/10.1246/cl.2006.682
Publication status	Published - 2006 Jun 5

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Cite this

Sueki, S., Igarashi, T., Nakajima, T., & Shimizu, I. (2006). Synthesis of β-amino ketones by iridium(III)-catalyzed direct-Mannich reaction. Chemistry Letters, 35(6), 682-683. https://doi.org/10.1246/cl.2006.682

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abstract = "The direct-Mannich reaction of ketones 1, aldehydes 2, and anilines 3 was studied using catalytic amount of transition-metal complexes. The trivalent iridium complex, [IrCl2(H)(COd)]2, catalyzed the direct-Mannich reaction effectively to give various β-amino kenotes in good yields under mild conditions.",

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10.1246/cl.2006.682