Synthesis of β-amino ketones by iridium(III)-catalyzed direct-Mannich reaction

Shunsuke Sueki, Takeyuki Igarashi, Takayuki Nakajima, Isao Shimizu

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6 Citations (Scopus)


The direct-Mannich reaction of ketones 1, aldehydes 2, and anilines 3 was studied using catalytic amount of transition-metal complexes. The trivalent iridium complex, [IrCl2(H)(COd)]2, catalyzed the direct-Mannich reaction effectively to give various β-amino kenotes in good yields under mild conditions.

Original languageEnglish
Pages (from-to)682-683
Number of pages2
JournalChemistry Letters
Issue number6
Publication statusPublished - 2006 Jun 5


ASJC Scopus subject areas

  • Chemistry(all)

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