Synthesis of ABC taxoid ring systems via a convergent strategy

K. C. Nicolaou, Zhen Yang, Erik J. Sorensen, Masahisa Nakada

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

Intermediates 4 and 5have been coupled via a Shapiro reaction to afford compound 6 which has been further elaborated to the ABCtaxcid systems 11and 12 via a McMurry pinacol cyclization to 11followed by oxidation to 12.

Original languageEnglish
Pages (from-to)1024-1026
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number12
DOIs
Publication statusPublished - 1993 Dec 1
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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