Synthesis of chiral α-acetoxy-N-acetylamides from chiral pyrimidylalkanols by the oxidative cleavage of pyrimidine ring

Shigehisa Tanji, Yasutaka Kodaka, Takanori Shibata, Kenso Soai

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Acetates of chiral 5-pyrimidylalkanols are transformed into chiral α- acetoxy-N-acetylamides and α-acetoxyamides without racemization in high total yields by the oxidative cleavage of pyrimidine ring using ruthenium tetroxide.

Original languageEnglish
Pages (from-to)151-158
Number of pages8
JournalHeterocycles
Volume52
Issue number1
DOIs
Publication statusPublished - 2000 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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