Abstract
Magnetic nanoparticles have been attracting much interest as a labeling material in the fields of advanced biological and medical applications such as drug delivery, magnetic resonance imaging, and array-based assaying. In this review, synthesis of iron oxide magnetic nanoparticles via a reverse micelle system and modification of their surface by an organosilane agent are discussed. Furthermore, as a practical biological assay system, the magnetic detection of biomolecular interactions is demonstrated by using the combination of a patterned substrate modified with a self-assembled monolayer and the magnetic nanoparticles.
| Original language | English |
|---|---|
| Pages (from-to) | 593-600 |
| Number of pages | 8 |
| Journal | Analytical and Bioanalytical Chemistry |
| Volume | 384 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2006 Feb 1 |
Keywords
- Biomolecule detection
- Iron oxide
- Magnetic nanoparticle
- Patterned surface
- Surface modification
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
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Osaka, T., Matsunaga, T., Nakanishi, T., Arakaki, A., Niwa, D., & Iida, H. (2006). Synthesis of magnetic nanoparticles and their application to bioassays. Analytical and Bioanalytical Chemistry, 384(3), 593-600. https://doi.org/10.1007/s00216-005-0255-7