Synthesis of polymerizable and amphiphilic (porphinato)irons and their copolymers with polymerizable phospholipid

Eishun Tsuchida, Hiroyuki Nishide, Makoto Yuasa, Takeshi Babe, Masaki Fukuzumi

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

This paper describes the synthesis of two polymerizable and amphiphilic porphyrins, and their copolymers with 1,2-bis(2′,4′-octadecadienoyl)-sn-glycero-3-phosphocholine. The two porphyrins and their (porphinato)iron derivatives have high compatibility with phospholipids and are efficiently copolymerized with the polymerizable phospholipid in a liposome state to give polymerized liposomes covalently containing the porphyrin residues. The oxygen-binding property of the copolymerized (porphinato)iron liposome is also described in comparison with that of a red blood cell.

Original languageEnglish
Pages (from-to)66-72
Number of pages7
JournalMacromolecules
Volume22
Issue number1
Publication statusPublished - 1989 Jan

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Liposomes
Phospholipids
Porphyrins
Copolymers
Iron
Blood
Cells
Oxygen
Derivatives

ASJC Scopus subject areas

  • Materials Chemistry

Cite this

Synthesis of polymerizable and amphiphilic (porphinato)irons and their copolymers with polymerizable phospholipid. / Tsuchida, Eishun; Nishide, Hiroyuki; Yuasa, Makoto; Babe, Takeshi; Fukuzumi, Masaki.

In: Macromolecules, Vol. 22, No. 1, 01.1989, p. 66-72.

Research output: Contribution to journalArticle

Tsuchida, Eishun ; Nishide, Hiroyuki ; Yuasa, Makoto ; Babe, Takeshi ; Fukuzumi, Masaki. / Synthesis of polymerizable and amphiphilic (porphinato)irons and their copolymers with polymerizable phospholipid. In: Macromolecules. 1989 ; Vol. 22, No. 1. pp. 66-72.
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