Synthesis of two Diastereoisomers of A/B Fragment of Ciguatoxin

Seijiro Hosokawa, Minoru Isobe

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Synthesis of 2 diastereoisomers of A/B fragments of ciguatoxin was achieved by connecting a hexose and 2 pentose derivatives with silylacetylene. The key steps are the cationic cyclization and reductive decomplexation of the acetylene biscobalthexacarbonyl complex.

Original languageEnglish
Pages (from-to)1179-1180
Number of pages2
JournalSynlett
Volume1995
Issue number11
DOIs
Publication statusPublished - 1995 Nov 1
Externally publishedYes

Fingerprint

Ciguatoxins
Pentoses
Acetylene
Hexoses
Cyclization
Derivatives

Keywords

  • Two diastereoisomers were synthesized from D-glucose and D-arabinose or L-xylose derivatives as partial model compounds for the A/B ring of ciguatoxin.

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of two Diastereoisomers of A/B Fragment of Ciguatoxin. / Hosokawa, Seijiro; Isobe, Minoru.

In: Synlett, Vol. 1995, No. 11, 01.11.1995, p. 1179-1180.

Research output: Contribution to journalArticle

Hosokawa, Seijiro ; Isobe, Minoru. / Synthesis of two Diastereoisomers of A/B Fragment of Ciguatoxin. In: Synlett. 1995 ; Vol. 1995, No. 11. pp. 1179-1180.
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