Synthetic studies on keramaphidin B: Formation of a macrocyclic ring by intramolecular Diels-Alder reaction

Hiroki Shimoda, Takahiro Shibata, Daisuke Sekine, Masahisa Nakada

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1 Citation (Scopus)

Abstract

The possibility of constructing the macrocyclic ring of keramaphidin B via an intramolecular Diels-Alder (IMDA) reaction has been investigated. The IMDA reaction of a substrate possessing dihydropyridone and diene moieties, which were tethered by an alkyl chain including a linear triple bond, was found to proceed in the presence of SnCl4 at 80 °C.

Original languageEnglish
Pages (from-to)3-11
Number of pages9
JournalHeterocycles
Volume100
Issue number1
DOIs
Publication statusPublished - 2020

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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