Tanzawaic acids A, B, C, and D: Inhibitors of superoxide anion production from Penicillium citrinum

Makoto Kuramoto, Kaoru Yamada, Mayumi Shikano, Kazunaga Yazawa, Hirokazu Arimoto, Tomoyuki Okamura, Daisuke Uemura

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)

Abstract

Tanzawaic acids have been isolated from Penicillium citrinum and their structures were elucidated by spectroscopic analysis. Their relative stereochemistries were also clarified by detailed analyses of 1H-1H coupling constants and NOE data. Tanzawaic acid B (GS-1302-1) significantly inhibits superoxide anion production in human neutrophils.

Original languageEnglish
Pages (from-to)885-886
Number of pages2
JournalChemistry Letters
Issue number9
Publication statusPublished - 1997
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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