Tanzawaic acids A, B, C, and D: Inhibitors of superoxide anion production from Penicillium citrinum

Makoto Kuramoto, Kaoru Yamada, Mayumi Shikano, Kazunaga Yazawa, Hirokazu Arimoto, Tomoyuki Okamura, Daisuke Uemura

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Abstract

Tanzawaic acids have been isolated from Penicillium citrinum and their structures were elucidated by spectroscopic analysis. Their relative stereochemistries were also clarified by detailed analyses of 1H-1H coupling constants and NOE data. Tanzawaic acid B (GS-1302-1) significantly inhibits superoxide anion production in human neutrophils.

Original languageEnglish
Pages (from-to)885-886
Number of pages2
JournalChemistry Letters
Issue number9
Publication statusPublished - 1997
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Kuramoto, M., Yamada, K., Shikano, M., Yazawa, K., Arimoto, H., Okamura, T., & Uemura, D. (1997). Tanzawaic acids A, B, C, and D: Inhibitors of superoxide anion production from Penicillium citrinum. Chemistry Letters, (9), 885-886.