The effect of combined exercise training on carotid artery structure and function, and vascular endothelial growth factor (VEGF) in obese older women

Jinkee Park, Yoshio Nakamura, Yoochan Kwon, Hyuntae Park, Eunhee Kim, Sangkab Park

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The purpose of this study was to examine the influence of 12-week combined exercise program on carotid artery structure and function, and vascular endothelial growth factor (VEGF) in obese older women. All subjects were sixty years or older (66.90±4.2 years), performed the combined exercise training during 12-week consisting of aerobic exercise, band exercise, and yoga exercise for 70 minutes 3 times a week under the supervision of exercise specialist. Despite no statistically significant change in control group, percent body fat mass (3.26 %, p<.01), systolic blood pressure (6.2 mmHg, p<.05), diastolic blood pressure (5.6 mmHg, p<.001), and 10 m maximal walking time (0.56 sec, p <.05), TC (20.5 mg/dl, p<.05), and LDL-C (22.16 mg/dl, p<.05) were significantly decreased respectively after 12-week combined exercise in exercise group. In addition, sit-and-reach (3.6 cm, p< .01), oxygen uptake per weight (3.27 ml/kg/min, p<.05), VEGF (17.85 pg/dl, p<.00l), and carotid artery LD (0.4 cm, p<.0l), PFV (10.06 cm/sec, p<.05), EFV (6.04 cm/sec, p<.05) were significantly increased in the exercise group than in the control group. The VEGF had the significant correlation with LD (r=.389, p<.01), PFV (r=.427, p<.01), EFV (r=.264, p<.05). In conclusion, 12-week combined exercise program is effective to improve and/or physical function and body composition. And also, exercise can improve serum lipid metabolism, VEGF regulation, and carotid artery function and structure.

Original languageEnglish
Pages (from-to)495-504
Number of pages10
Journaljapanese journal of physical fitness and sports medicine
Volume59
Issue number5
DOIs
Publication statusPublished - 2010 Oct

Keywords

  • Carotid artery structure and function
  • Combined exercise training
  • Obese
  • Vascular endothelial growth factor

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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