The effect of isobutylmethylxanthine on the photoresponse and phosphorylation of phosphatidylinositol in octopus retina

Tohru Yoshioka, Hiroko Inoue, Masayuki Takagi, Fumio Hayashi, Taisaku Amakawa

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The effect of isobutylmethylxanthine on the photoresponse and the phosphorylation of phosphatidylinositol was studied. The recovery of photoresponse after a bright flash was greatly altered by the addition of isobutylmethylxanthine. Phosphatidylinositol phosphorylation, assessed by the incorporation of label from [γ-32P]ATP, was influenced by isobutylmethylxanthine. Incorporation of 32P was decreased into diphosphoinositide and triphosphoinositide, and increased into phosphatidic acid. These changes were interpreted by indroducing a parameter, Ψ, calcium charge of the plasma membrane.

Original languageEnglish
Pages (from-to)50-55
Number of pages6
JournalBBA - General Subjects
Issue number1
Publication statusPublished - 1983 Jan 4
Externally publishedYes



  • (Octopus retina)
  • Isobutylmethylxanthine
  • Phosphatidylinositol
  • Phosphorylation
  • Photoresponse

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology
  • Medicine(all)

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