TY - JOUR
T1 - The effects of Lactobacillus gasseri OLL2809 intake on oral immune function in college rugby athletes
AU - Hanaoka, Yukichi
AU - Shimizu, Kazuhiro
AU - Washiya, Kosuke
AU - Tamura, Akira
AU - Takemura, Masahiro
AU - Furukawa, Takuo
AU - Miyamoto, Toshikazu
AU - Watanabe, Koichi
AU - Akama, Takao
PY - 2015/1/1
Y1 - 2015/1/1
N2 - The purpose of this study was to investigate the effects of Lactobacillus gasseri OLL2809 (MG2809) intake on salivary secretory immunoglobulin A (SIgA) secretion and incidence of upper-respiratory tract infection (URTI) symptoms among college rugby athletes. Sixty-seven subjects were assigned to a MG2809 group (n = 33) or a placebo group (n = 34) using a double-blind procedure. Each subject took MG2809 or placebo tablets for 9 weeks. Resting saliva samples were collected before (0 week) and after 2, 4, 6, 8, and 9 weeks of the MG2809 intakes. A log of URTI symptoms was kept every day during the study period. Our results showed that salivary SIgA level was significantly increased at 6 weeks in the MG2809 group (p < 0.05), although the placebo group did not show significant change. The duration of URTI symptoms episode in the MG2809 group was significantly shorter than that in the placebo (p < 0.05). These results suggest that regular intake of MG2809 may enhance oral immune function mediated by SIgA and reduce the risk of URTI in athletes.
AB - The purpose of this study was to investigate the effects of Lactobacillus gasseri OLL2809 (MG2809) intake on salivary secretory immunoglobulin A (SIgA) secretion and incidence of upper-respiratory tract infection (URTI) symptoms among college rugby athletes. Sixty-seven subjects were assigned to a MG2809 group (n = 33) or a placebo group (n = 34) using a double-blind procedure. Each subject took MG2809 or placebo tablets for 9 weeks. Resting saliva samples were collected before (0 week) and after 2, 4, 6, 8, and 9 weeks of the MG2809 intakes. A log of URTI symptoms was kept every day during the study period. Our results showed that salivary SIgA level was significantly increased at 6 weeks in the MG2809 group (p < 0.05), although the placebo group did not show significant change. The duration of URTI symptoms episode in the MG2809 group was significantly shorter than that in the placebo (p < 0.05). These results suggest that regular intake of MG2809 may enhance oral immune function mediated by SIgA and reduce the risk of URTI in athletes.
KW - Athlete
KW - Exercise
KW - Lactic acid bacteria
KW - MG2809
KW - Secretory immunoglobulin A
UR - http://www.scopus.com/inward/record.url?scp=84929899841&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929899841&partnerID=8YFLogxK
U2 - 10.7600/jspfsm.64.315
DO - 10.7600/jspfsm.64.315
M3 - Article
AN - SCOPUS:84929899841
VL - 64
SP - 315
EP - 322
JO - Japanese Journal of Physical Fitness and Sports Medicine
JF - Japanese Journal of Physical Fitness and Sports Medicine
SN - 0039-906X
IS - 3
ER -