Abstract
The discovery of non-universal genetic codes in several mitochondria and nuclear systems during the past ten years has necessitated a reconsideration of the concept that the genetic code is universal and frozen, as was once believed. Here, the flexibility of the relationship between codons and amino acids is discussed on the basis of the distribution of non-universal genetic codes in various organisms insofar as has been observed to date. Judging from the result of recent investigations into tRNA identity, it would appear that the non-participation of the anticodon in recognition by aminoacyl-tRNA synthetase has significantly influenced the variability of codons.
| Original language | English |
|---|---|
| Pages (from-to) | 345-364 |
| Number of pages | 20 |
| Journal | Origins of Life and Evolution of the Biosphere |
| Volume | 23 |
| Issue number | 5-6 |
| DOIs | |
| Publication status | Published - 1993 Dec 1 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ecology, Evolution, Behavior and Systematics
- Space and Planetary Science
Cite this
The evolutionary change of the genetic code as restricted by the anticodon and identity of transfer RNA. / Ueda, Takuya; Watanabe, Kimitsuna.
In: Origins of Life and Evolution of the Biosphere, Vol. 23, No. 5-6, 01.12.1993, p. 345-364.Research output: Contribution to journal › Article
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TY - JOUR
T1 - The evolutionary change of the genetic code as restricted by the anticodon and identity of transfer RNA
AU - Ueda, Takuya
AU - Watanabe, Kimitsuna
PY - 1993/12/1
Y1 - 1993/12/1
N2 - The discovery of non-universal genetic codes in several mitochondria and nuclear systems during the past ten years has necessitated a reconsideration of the concept that the genetic code is universal and frozen, as was once believed. Here, the flexibility of the relationship between codons and amino acids is discussed on the basis of the distribution of non-universal genetic codes in various organisms insofar as has been observed to date. Judging from the result of recent investigations into tRNA identity, it would appear that the non-participation of the anticodon in recognition by aminoacyl-tRNA synthetase has significantly influenced the variability of codons.
AB - The discovery of non-universal genetic codes in several mitochondria and nuclear systems during the past ten years has necessitated a reconsideration of the concept that the genetic code is universal and frozen, as was once believed. Here, the flexibility of the relationship between codons and amino acids is discussed on the basis of the distribution of non-universal genetic codes in various organisms insofar as has been observed to date. Judging from the result of recent investigations into tRNA identity, it would appear that the non-participation of the anticodon in recognition by aminoacyl-tRNA synthetase has significantly influenced the variability of codons.
UR - http://www.scopus.com/inward/record.url?scp=0027745420&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027745420&partnerID=8YFLogxK
U2 - 10.1007/BF01582085
DO - 10.1007/BF01582085
M3 - Article
VL - 23
SP - 345
EP - 364
JO - Origins of Life and Evolution of Biospheres
JF - Origins of Life and Evolution of Biospheres
SN - 0169-6149
IS - 5-6
ER -