The first total synthesis and structural determination of actinopyrone A

Seijiro Hosokawa, Kazuya Yokota, Keisuke Imamura, Yasuaki Suzuki, Masataka Kawarasaki, Kuniaki Tatsuta

    Research output: Contribution to journal › Article

    33 Citations (Scopus)

    Abstract

    Actinopyrone A (1) has been synthesized by using our developed remote stereoinduction, Kocienski olefination, Horner-Wadsworth-Emmons olefination, and reductive de-conjugation of the vinylpyrone. A concise method of O-methylation to obtain the γ-pyrone has also been established.

    Original languageEnglish
    Pages (from-to)5415-5418
    Number of pages4
    JournalTetrahedron Letters
    Volume47
    Issue number30
    DOIs
    Publication statusPublished - 2006 Jul 24

    Fingerprint

    Pyrones
    Methylation
    actinopyrone A

    Keywords

    • 4-Pyrone
    • Actinopyrone A
    • Reductive de-conjugation
    • Remote stereoinduction
    • Structural determination
    • Total synthesis

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    Hosokawa, S., Yokota, K., Imamura, K., Suzuki, Y., Kawarasaki, M., & Tatsuta, K. (2006). The first total synthesis and structural determination of actinopyrone A. Tetrahedron Letters, 47(30), 5415-5418. https://doi.org/10.1016/j.tetlet.2006.05.028

    The first total synthesis and structural determination of actinopyrone A. / Hosokawa, Seijiro; Yokota, Kazuya; Imamura, Keisuke; Suzuki, Yasuaki; Kawarasaki, Masataka; Tatsuta, Kuniaki.

    In: Tetrahedron Letters, Vol. 47, No. 30, 24.07.2006, p. 5415-5418.

    Research output: Contribution to journal › Article

    Hosokawa, S, Yokota, K, Imamura, K, Suzuki, Y, Kawarasaki, M & Tatsuta, K 2006, 'The first total synthesis and structural determination of actinopyrone A', Tetrahedron Letters, vol. 47, no. 30, pp. 5415-5418. https://doi.org/10.1016/j.tetlet.2006.05.028
    Hosokawa S, Yokota K, Imamura K, Suzuki Y, Kawarasaki M, Tatsuta K. The first total synthesis and structural determination of actinopyrone A. Tetrahedron Letters. 2006 Jul 24;47(30):5415-5418. https://doi.org/10.1016/j.tetlet.2006.05.028
    Hosokawa, Seijiro ; Yokota, Kazuya ; Imamura, Keisuke ; Suzuki, Yasuaki ; Kawarasaki, Masataka ; Tatsuta, Kuniaki. / The first total synthesis and structural determination of actinopyrone A. In: Tetrahedron Letters. 2006 ; Vol. 47, No. 30. pp. 5415-5418.
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    AU - Tatsuta, Kuniaki

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