The first total synthesis and structural determination of actinopyrone A

Seijiro Hosokawa; Kazuya Yokota; Keisuke Imamura; Yasuaki Suzuki; Masataka Kawarasaki; Kuniaki Tatsuta

doi:10.1016/j.tetlet.2006.05.028

The first total synthesis and structural determination of actinopyrone A

Seijiro Hosokawa, Kazuya Yokota, Keisuke Imamura, Yasuaki Suzuki, Masataka Kawarasaki, Kuniaki Tatsuta

School of Advanced Science and Engineering

Research output: Contribution to journal › Article

36 Citations (Scopus)

Abstract

Actinopyrone A (1) has been synthesized by using our developed remote stereoinduction, Kocienski olefination, Horner-Wadsworth-Emmons olefination, and reductive de-conjugation of the vinylpyrone. A concise method of O-methylation to obtain the γ-pyrone has also been established.

Original language	English
Pages (from-to)	5415-5418
Number of pages	4
Journal	Tetrahedron Letters
Volume	47
Issue number	30
DOIs	https://doi.org/10.1016/j.tetlet.2006.05.028
Publication status	Published - 2006 Jul 24

Keywords

4-Pyrone
Actinopyrone A
Reductive de-conjugation
Remote stereoinduction
Structural determination
Total synthesis

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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Hosokawa, S., Yokota, K., Imamura, K., Suzuki, Y., Kawarasaki, M., & Tatsuta, K. (2006). The first total synthesis and structural determination of actinopyrone A. Tetrahedron Letters, 47(30), 5415-5418. https://doi.org/10.1016/j.tetlet.2006.05.028

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AU - Imamura, Keisuke

AU - Suzuki, Yasuaki

AU - Kawarasaki, Masataka

AU - Tatsuta, Kuniaki

PY - 2006/7/24

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