The first total synthesis and structural determination of actinopyrone A

Seijiro Hosokawa, Kazuya Yokota, Keisuke Imamura, Yasuaki Suzuki, Masataka Kawarasaki, Kuniaki Tatsuta

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Actinopyrone A (1) has been synthesized by using our developed remote stereoinduction, Kocienski olefination, Horner-Wadsworth-Emmons olefination, and reductive de-conjugation of the vinylpyrone. A concise method of O-methylation to obtain the γ-pyrone has also been established.

Original languageEnglish
Pages (from-to)5415-5418
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number30
DOIs
Publication statusPublished - 2006 Jul 24

Keywords

  • 4-Pyrone
  • Actinopyrone A
  • Reductive de-conjugation
  • Remote stereoinduction
  • Structural determination
  • Total synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'The first total synthesis and structural determination of actinopyrone A'. Together they form a unique fingerprint.

  • Cite this

    Hosokawa, S., Yokota, K., Imamura, K., Suzuki, Y., Kawarasaki, M., & Tatsuta, K. (2006). The first total synthesis and structural determination of actinopyrone A. Tetrahedron Letters, 47(30), 5415-5418. https://doi.org/10.1016/j.tetlet.2006.05.028