The first total synthesis and structural determination of benzopyrenomycin

Seijiro Hosokawa, Yuki Mukaeda, Ryo Kawahara, Kuniaki Tatsuta

    Research output: Contribution to journalArticle

    16 Citations (Scopus)

    Abstract

    The first total synthesis and structural determination of benzopyrenomycin has been achieved. This synthesis contains remarkable transformations including cyclization to afford the benzanthrone skeleton, syn-selective vinylogous Mukaiyama aldol reaction, and radical cyclization with the benzanthrone attaching the iodoalkane chain.

    Original languageEnglish
    Pages (from-to)6701-6704
    Number of pages4
    JournalTetrahedron Letters
    Volume50
    Issue number48
    DOIs
    Publication statusPublished - 2009 Dec 2

    Fingerprint

    Cyclization
    Skeleton
    benzopyrenomycin
    benzanthrone
    3-hydroxybutanal

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    The first total synthesis and structural determination of benzopyrenomycin. / Hosokawa, Seijiro; Mukaeda, Yuki; Kawahara, Ryo; Tatsuta, Kuniaki.

    In: Tetrahedron Letters, Vol. 50, No. 48, 02.12.2009, p. 6701-6704.

    Research output: Contribution to journalArticle

    Hosokawa, Seijiro ; Mukaeda, Yuki ; Kawahara, Ryo ; Tatsuta, Kuniaki. / The first total synthesis and structural determination of benzopyrenomycin. In: Tetrahedron Letters. 2009 ; Vol. 50, No. 48. pp. 6701-6704.
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