The first total synthesis and structural determination of lagunamycin

Seijiro Hosokawa, Shoichi Kuroda, Keisuke Imamura, Kuniaki Tatsuta

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Lagunamycin (1) has been synthesized by using our developed remote stereoinduction, Knorr condensation, periodinane oxidation, and diazonation. This enantioselective synthesis determined the absolute configuration of lagunamycin. Existence of rotational conformers was confirmed by NMR studies.

Original languageEnglish
Pages (from-to)6183-6186
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number35
DOIs
Publication statusPublished - 2006 Aug 28

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'The first total synthesis and structural determination of lagunamycin'. Together they form a unique fingerprint.

  • Cite this