The first total synthesis of trichostatin D

Seijiro Hosokawa, Takashi Ogura, Hidetaka Togashi, Kuniaki Tatsuta

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Trichostatin D and 6-epi-trichostatin D have been stereoselectively synthesized through a remote stereoinduction with a chiral vinylketene silyl N,O-acetal and glycosylation of hydroxyimide under Mitsunobu conditions.

Original languageEnglish
Pages (from-to)333-337
Number of pages5
JournalTetrahedron Letters
Volume46
Issue number2
DOIs
Publication statusPublished - 2005 Jan 10

Keywords

  • Glycosylation
  • Total synthesis
  • Trichostatin D
  • Vinylketene silyl N,O-acetal

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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