The first total synthesis of trichostatin D

Seijiro Hosokawa, Takashi Ogura, Hidetaka Togashi, Kuniaki Tatsuta

    Research output: Contribution to journalArticle

    50 Citations (Scopus)

    Abstract

    Trichostatin D and 6-epi-trichostatin D have been stereoselectively synthesized through a remote stereoinduction with a chiral vinylketene silyl N,O-acetal and glycosylation of hydroxyimide under Mitsunobu conditions.

    Original languageEnglish
    Pages (from-to)333-337
    Number of pages5
    JournalTetrahedron Letters
    Volume46
    Issue number2
    DOIs
    Publication statusPublished - 2005 Jan 10

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    Glycosylation
    Acetals
    trichostatin D

    Keywords

    • Glycosylation
    • Total synthesis
    • Trichostatin D
    • Vinylketene silyl N,O-acetal

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    The first total synthesis of trichostatin D. / Hosokawa, Seijiro; Ogura, Takashi; Togashi, Hidetaka; Tatsuta, Kuniaki.

    In: Tetrahedron Letters, Vol. 46, No. 2, 10.01.2005, p. 333-337.

    Research output: Contribution to journalArticle

    Hosokawa, Seijiro ; Ogura, Takashi ; Togashi, Hidetaka ; Tatsuta, Kuniaki. / The first total synthesis of trichostatin D. In: Tetrahedron Letters. 2005 ; Vol. 46, No. 2. pp. 333-337.
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