The gonadotropin-inhibitory hormone: What we know and what we still have to learn from fish

María P. Di Yorio, José A. Muñoz-Cueto, José A. Paullada-Salmerón, Gustavo M. Somoza, Kazuyoshi Tsutsui, Paula G. Vissio

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Gonadotropin-inhibitory hormone, GnIH, is named because of its function in birds and mammals; however, in other vertebrates this function is not yet clearly established. More than half of the vertebrate species are teleosts. This group is characterized by the 3R whole genome duplication, a fact that could have been responsible for the great phenotypic complexity and great variability in reproductive strategies and sexual behavior. In this context, we revise GnIH cell bodies and fibers distribution in adult brains of teleosts, discuss its relationship with GnRH variants and summarize the few reports available about the ontogeny of the GnIH system. Considering all the information presented in this review, we propose that in teleosts, GnIH could have other functions beyond reproduction or act as an integrative signal in the reproductive process. However, further studies are required in order to clarify the role of GnIH in this group including its involvement in development, a key stage that strongly impacts on adult life.

Original languageEnglish
Article number78
JournalFrontiers in Endocrinology
Volume10
Issue numberFEB
DOIs
Publication statusPublished - 2019 Jan 1

Fingerprint

Gonadotropins
Vertebrates
Fishes
Hormones
Reproductive Behavior
Gonadotropin-Releasing Hormone
Sexual Behavior
Birds
Reproduction
Mammals
Genome
Brain
Cell Body

Keywords

  • Brain
  • Fish
  • GnIH
  • GnRH
  • Growth
  • Ontogeny
  • Reproduction

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

Cite this

Di Yorio, M. P., Muñoz-Cueto, J. A., Paullada-Salmerón, J. A., Somoza, G. M., Tsutsui, K., & Vissio, P. G. (2019). The gonadotropin-inhibitory hormone: What we know and what we still have to learn from fish. Frontiers in Endocrinology, 10(FEB), [78]. https://doi.org/10.3389/fendo.2019.00078

The gonadotropin-inhibitory hormone : What we know and what we still have to learn from fish. / Di Yorio, María P.; Muñoz-Cueto, José A.; Paullada-Salmerón, José A.; Somoza, Gustavo M.; Tsutsui, Kazuyoshi; Vissio, Paula G.

In: Frontiers in Endocrinology, Vol. 10, No. FEB, 78, 01.01.2019.

Research output: Contribution to journalReview article

Di Yorio, MP, Muñoz-Cueto, JA, Paullada-Salmerón, JA, Somoza, GM, Tsutsui, K & Vissio, PG 2019, 'The gonadotropin-inhibitory hormone: What we know and what we still have to learn from fish', Frontiers in Endocrinology, vol. 10, no. FEB, 78. https://doi.org/10.3389/fendo.2019.00078
Di Yorio, María P. ; Muñoz-Cueto, José A. ; Paullada-Salmerón, José A. ; Somoza, Gustavo M. ; Tsutsui, Kazuyoshi ; Vissio, Paula G. / The gonadotropin-inhibitory hormone : What we know and what we still have to learn from fish. In: Frontiers in Endocrinology. 2019 ; Vol. 10, No. FEB.
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