The impact of Uva tea extract capsule consumption on psychological stress: A randomized, double-blind, placebo-controlled, crossover trial

Naoko Takamizawa, Shirrichiro Yamashita, Naoko Suzuki, Kazuo Yamamoto, Haruko Takeyama, Kazunaga Yazawa, Tsuyoshi Takara

Research output: Contribution to journalArticle

Abstract

Objectives: This study aims to investigate the effects of consuming Uva tea extract capsules by decreasing the psychological stress in Japanese subjects. Methods: Twenty-two eligible subjects were randomly assigned to sequences either an Uva tea extract (Uva) or a placebo, with each member in both sequences consuming appropriate capsules. Each intervention lasted for 3 weeks, with the 2-week washout period. We assessed the autonomic nervous activity and mood state of subjects in both sequences. Results: The Uva capsule intake revealed trends toward significantly lower the ratio between low and high frequency components and significantly lower tension-anxiety compared with the placebo capsule intake. Furthermore, subjects with the body mass index <25, especially the Uva capsule intake, exhibited the dominant parasympathetic nervous system. Conclusions: Hence, this study suggests that the 3-week Uva capsule consumption could modulate the automatic nervous system and ease tension and anxiety. Trial Registration University Hospital Medical Information Network; UMIN000027549 Foundation There was no funding.

Original languageEnglish
Pages (from-to)2001-2010
Number of pages10
JournalJapanese Pharmacology and Therapeutics
Volume46
Issue number12
Publication statusPublished - 2018 Jan 1

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Tea
Psychological Stress
Cross-Over Studies
Capsules
Placebos
Anxiety
Parasympathetic Nervous System
Information Services
Nervous System
Body Mass Index

Keywords

  • Autonomic nervous activity
  • Parasympathetic nervous system
  • Polyphenol
  • Theaflavin
  • Uva tea

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

The impact of Uva tea extract capsule consumption on psychological stress : A randomized, double-blind, placebo-controlled, crossover trial. / Takamizawa, Naoko; Yamashita, Shirrichiro; Suzuki, Naoko; Yamamoto, Kazuo; Takeyama, Haruko; Yazawa, Kazunaga; Takara, Tsuyoshi.

In: Japanese Pharmacology and Therapeutics, Vol. 46, No. 12, 01.01.2018, p. 2001-2010.

Research output: Contribution to journalArticle

Takamizawa, Naoko ; Yamashita, Shirrichiro ; Suzuki, Naoko ; Yamamoto, Kazuo ; Takeyama, Haruko ; Yazawa, Kazunaga ; Takara, Tsuyoshi. / The impact of Uva tea extract capsule consumption on psychological stress : A randomized, double-blind, placebo-controlled, crossover trial. In: Japanese Pharmacology and Therapeutics. 2018 ; Vol. 46, No. 12. pp. 2001-2010.
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