The Influence of Compression Socks During a Marathon on Exercise-Associated Muscle Damage

Amanda L. Zaleski, Linda S. Pescatello, Kevin D. Ballard, Gregory A. Panza, William Adams, Yuri Hosokawa, Paul D. Thompson, Beth A. Taylor

Research output: Contribution to journalArticle

Abstract

CONTEXT: Compression socks have become increasingly popular with athletes due to perceived enhancement of exercise performance and recovery. However, research examining the efficacy of compression socks to reduce exercise-associated muscle damage has been equivocal, with few direct measurements of markers of muscle damage. OBJECTIVE: To examine the influence of compression socks worn during a marathon on creatine kinase (CK) levels. DESIGN: A randomized controlled trial. SETTING: 2013 Hartford Marathon, Hartford, CT. PARTICIPANTS: Adults (n = 20) randomized to control (CONTROL; n = 10) or compression sock (SOCK; n = 10) groups. MAIN OUTCOME MEASURES: Blood samples were collected 24 hours before, immediately after, and 24 hours following the marathon for the analysis of CK, a marker of muscle damage. RESULTS: Baseline CK levels did not differ between CONTROL (89.3 [41.2] U/L) and SOCK (100.0 [56.2] U/L) (P = .63). Immediately following the marathon (≤1 h), CK increased 273% from baseline (P < .001 for time), with no difference in exercise-induced changes in CK from baseline between CONTROL (+293.9 [278.2] U/L) and SOCK (+233.1 [225.3] U/L; P = .60 for time × group). The day following the marathon (≤24 h), CK further increased 1094% from baseline (P < .001 for time), with no difference in changes in CK from baseline between CONTROL (+ 1191.9 [1194.8] U/L) and SOCK (+889.1 [760.2] U/L; P = .53 for time × group). These similar trends persisted despite controlling for potential covariates such as age, body mass index, and race finishing time (Ps > .29). CONCLUSIONS: Compression socks worn during a marathon do not appear to mitigate objectively measured markers of muscle damage immediately following and 24 hours after a marathon.

Original languageEnglish
Pages (from-to)724-728
Number of pages5
JournalJournal of sport rehabilitation
Volume28
Issue number7
DOIs
Publication statusPublished - 2019 Sep 1

Keywords

  • creatine kinase
  • endurance exercise
  • marathon-induced
  • mechanical prophylaxis

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

Fingerprint Dive into the research topics of 'The Influence of Compression Socks During a Marathon on Exercise-Associated Muscle Damage'. Together they form a unique fingerprint.

  • Cite this

    Zaleski, A. L., Pescatello, L. S., Ballard, K. D., Panza, G. A., Adams, W., Hosokawa, Y., Thompson, P. D., & Taylor, B. A. (2019). The Influence of Compression Socks During a Marathon on Exercise-Associated Muscle Damage. Journal of sport rehabilitation, 28(7), 724-728. https://doi.org/10.1123/jsr.2018-0060