Abstract
Four cyclic peptides, kapakahines A-D, were isolated from the marine sponge Cribrochalina olemda. Their structures including complete stereochemistry were elucidated by spectral analysis and chemical degradation. The unique structural feature of these peptides is the lack of an amide linkage between two tryptophan residues. Instead the ring is closed by a bond from the indole nitrogen of Trp-1 to the β-carbon of Trp-2.
| Original language | English |
|---|---|
| Pages (from-to) | 7168-7173 |
| Number of pages | 6 |
| Journal | Journal of Organic Chemistry |
| Volume | 61 |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - 1996 Jan 1 |
| Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry
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Cite this
Yeung, B. K. S., Nakao, Y., Kinnel, R. B., Carney, J. R., Yoshida, W. Y., Scheuer, P. J., & Kelly-Borges, M. (1996). The kapakahines, cyclic peptides from the marine sponge Cribrochalina olemda. Journal of Organic Chemistry, 61(20), 7168-7173. https://doi.org/10.1021/jo960725e