The role of calcium ions in circadian rhythm of suprachiasmatic nucleus neuron activity in rat hypothalamic slices

Shigenobu Shibata, Akiko Shiratsuchi, Shyh Yuh Liou, Showa Ueki

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The role of calcium ions in maintaining the circadian rhythm of suprachiasmatic nucleus (SCN) neuron activity was investigated using rat hypothalamic slice preparations. In normal Krebs solution, the firing rate of SCN neurons was higher in the light period than in the dark period. In Ca2+ -free Krebs solution, SCN neuron activity was low during all periods and did not show diurnal rhythm. These results suggest that the disappearance of circadian rhythmic change of SCN neuron activity in Ca2+ -free Krebs solution may be due to the disappearance of synaptic transmission in the SCN.

Original languageEnglish
Pages (from-to)181-184
Number of pages4
JournalNeuroscience Letters
Volume52
Issue number1-2
DOIs
Publication statusPublished - 1984 Nov 23
Externally publishedYes

Fingerprint

Suprachiasmatic Nucleus
Circadian Rhythm
Ions
Calcium
Neurons
Synaptic Transmission
Light
Krebs-Ringer solution

Keywords

  • calcium ions
  • circadian rhythm
  • rat brain slice
  • single unit activity
  • suprachiasmatic nucleus
  • synaptic transmission

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The role of calcium ions in circadian rhythm of suprachiasmatic nucleus neuron activity in rat hypothalamic slices. / Shibata, Shigenobu; Shiratsuchi, Akiko; Liou, Shyh Yuh; Ueki, Showa.

In: Neuroscience Letters, Vol. 52, No. 1-2, 23.11.1984, p. 181-184.

Research output: Contribution to journalArticle

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