The role of mesencephalic tegmentum in regulating female rat sexual behaviors

Korehito Yamanouchi, Yasumasa Arai

    Research output: Contribution to journalArticle

    20 Citations (Scopus)

    Abstract

    Feminine sexual behaviors were tested in estradiol benzoate (EB) and progesterone (P) primed ovariectomized rats following four types of radiofrequency lesions in the midbrain tegmentum. The dorsomedial lesion (DML) which destroyed the ventromedial central gray including the dorsal raphe nucleus and adjacent area induced high sexual receptivity in the females primed with low dose (0.5 μg) of EB-P. All females with DML exhibited lordosis and ear wiggling, the mean lordosis quotient (LQ) being significantly higher than that of castrated controls or sham operated rats. Sexual receptivity in females with ventromedial tegmental lesion was not significantly different from those of the control and sham groups. In contrast to the medially lesioned groups, the mean LQ was low in the animals with bilateral lateral tegmental lesions even when the dose of EB was increased to 2 μg which was sufficient to induce high sexual receptivity in castrated and sham operated control females. In the animals with dorsolateral tegmental lesions (DLL), a much more severe loss of lordosis was seen than in those with ventrolateral tegmental lesions (VLL). None of the DLL females displayed sexual behavior throughout the present experiments. These results lead us to conclude that the midbrain dorsomedial tegmental area (ventral central gray and the adjacent area) is concerned with female sexual behavior inhibiting system, whereas the lateral tegmental area may be involved in the facilitatory system.

    Original languageEnglish
    Pages (from-to)255-259
    Number of pages5
    JournalPhysiology and Behavior
    Volume35
    Issue number2
    DOIs
    Publication statusPublished - 1985

    Fingerprint

    Tegmentum Mesencephali
    Sexual Behavior
    Lordosis
    Ventral Tegmental Area
    Mesencephalon
    Ear
    Control Groups

    Keywords

    • Estrogen
    • Female rat
    • Lordosis
    • Lordosis inhibiting system
    • Midbrain tegmentum
    • Progesterone
    • Soliciting behavior
    • Ventral central gray

    ASJC Scopus subject areas

    • Physiology (medical)
    • Behavioral Neuroscience

    Cite this

    The role of mesencephalic tegmentum in regulating female rat sexual behaviors. / Yamanouchi, Korehito; Arai, Yasumasa.

    In: Physiology and Behavior, Vol. 35, No. 2, 1985, p. 255-259.

    Research output: Contribution to journalArticle

    Yamanouchi, Korehito ; Arai, Yasumasa. / The role of mesencephalic tegmentum in regulating female rat sexual behaviors. In: Physiology and Behavior. 1985 ; Vol. 35, No. 2. pp. 255-259.
    @article{2f69463e4db6422784c2903c15266c60,
    title = "The role of mesencephalic tegmentum in regulating female rat sexual behaviors",
    abstract = "Feminine sexual behaviors were tested in estradiol benzoate (EB) and progesterone (P) primed ovariectomized rats following four types of radiofrequency lesions in the midbrain tegmentum. The dorsomedial lesion (DML) which destroyed the ventromedial central gray including the dorsal raphe nucleus and adjacent area induced high sexual receptivity in the females primed with low dose (0.5 μg) of EB-P. All females with DML exhibited lordosis and ear wiggling, the mean lordosis quotient (LQ) being significantly higher than that of castrated controls or sham operated rats. Sexual receptivity in females with ventromedial tegmental lesion was not significantly different from those of the control and sham groups. In contrast to the medially lesioned groups, the mean LQ was low in the animals with bilateral lateral tegmental lesions even when the dose of EB was increased to 2 μg which was sufficient to induce high sexual receptivity in castrated and sham operated control females. In the animals with dorsolateral tegmental lesions (DLL), a much more severe loss of lordosis was seen than in those with ventrolateral tegmental lesions (VLL). None of the DLL females displayed sexual behavior throughout the present experiments. These results lead us to conclude that the midbrain dorsomedial tegmental area (ventral central gray and the adjacent area) is concerned with female sexual behavior inhibiting system, whereas the lateral tegmental area may be involved in the facilitatory system.",
    keywords = "Estrogen, Female rat, Lordosis, Lordosis inhibiting system, Midbrain tegmentum, Progesterone, Soliciting behavior, Ventral central gray",
    author = "Korehito Yamanouchi and Yasumasa Arai",
    year = "1985",
    doi = "10.1016/0031-9384(85)90346-4",
    language = "English",
    volume = "35",
    pages = "255--259",
    journal = "Physiology and Behavior",
    issn = "0031-9384",
    publisher = "Elsevier Inc.",
    number = "2",

    }

    TY - JOUR

    T1 - The role of mesencephalic tegmentum in regulating female rat sexual behaviors

    AU - Yamanouchi, Korehito

    AU - Arai, Yasumasa

    PY - 1985

    Y1 - 1985

    N2 - Feminine sexual behaviors were tested in estradiol benzoate (EB) and progesterone (P) primed ovariectomized rats following four types of radiofrequency lesions in the midbrain tegmentum. The dorsomedial lesion (DML) which destroyed the ventromedial central gray including the dorsal raphe nucleus and adjacent area induced high sexual receptivity in the females primed with low dose (0.5 μg) of EB-P. All females with DML exhibited lordosis and ear wiggling, the mean lordosis quotient (LQ) being significantly higher than that of castrated controls or sham operated rats. Sexual receptivity in females with ventromedial tegmental lesion was not significantly different from those of the control and sham groups. In contrast to the medially lesioned groups, the mean LQ was low in the animals with bilateral lateral tegmental lesions even when the dose of EB was increased to 2 μg which was sufficient to induce high sexual receptivity in castrated and sham operated control females. In the animals with dorsolateral tegmental lesions (DLL), a much more severe loss of lordosis was seen than in those with ventrolateral tegmental lesions (VLL). None of the DLL females displayed sexual behavior throughout the present experiments. These results lead us to conclude that the midbrain dorsomedial tegmental area (ventral central gray and the adjacent area) is concerned with female sexual behavior inhibiting system, whereas the lateral tegmental area may be involved in the facilitatory system.

    AB - Feminine sexual behaviors were tested in estradiol benzoate (EB) and progesterone (P) primed ovariectomized rats following four types of radiofrequency lesions in the midbrain tegmentum. The dorsomedial lesion (DML) which destroyed the ventromedial central gray including the dorsal raphe nucleus and adjacent area induced high sexual receptivity in the females primed with low dose (0.5 μg) of EB-P. All females with DML exhibited lordosis and ear wiggling, the mean lordosis quotient (LQ) being significantly higher than that of castrated controls or sham operated rats. Sexual receptivity in females with ventromedial tegmental lesion was not significantly different from those of the control and sham groups. In contrast to the medially lesioned groups, the mean LQ was low in the animals with bilateral lateral tegmental lesions even when the dose of EB was increased to 2 μg which was sufficient to induce high sexual receptivity in castrated and sham operated control females. In the animals with dorsolateral tegmental lesions (DLL), a much more severe loss of lordosis was seen than in those with ventrolateral tegmental lesions (VLL). None of the DLL females displayed sexual behavior throughout the present experiments. These results lead us to conclude that the midbrain dorsomedial tegmental area (ventral central gray and the adjacent area) is concerned with female sexual behavior inhibiting system, whereas the lateral tegmental area may be involved in the facilitatory system.

    KW - Estrogen

    KW - Female rat

    KW - Lordosis

    KW - Lordosis inhibiting system

    KW - Midbrain tegmentum

    KW - Progesterone

    KW - Soliciting behavior

    KW - Ventral central gray

    UR - http://www.scopus.com/inward/record.url?scp=0022179207&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0022179207&partnerID=8YFLogxK

    U2 - 10.1016/0031-9384(85)90346-4

    DO - 10.1016/0031-9384(85)90346-4

    M3 - Article

    C2 - 4070393

    AN - SCOPUS:0022179207

    VL - 35

    SP - 255

    EP - 259

    JO - Physiology and Behavior

    JF - Physiology and Behavior

    SN - 0031-9384

    IS - 2

    ER -