The splice variant Ntr encoded by the tobacco resistance gene N has arole for negative regulation of antiviral defense responses

Nobumitsu Sasaki, Masumi Takaoka, Shobu Sasaki, Katsuyuki Hirai, Tetsuo Meshi, Hiroshi Nyunoya

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Tobamovirus infection or transient elicitor expression induces a hypersensitive response (HR) in tobacco plants carrying the N resistance gene, which produces two gene products (N and Ntr) through alternative splicing. In this study, the biological significance of Ntr was investigated. The transient overexpression of Ntr markedly inhibited the induction of HR and N-dependent antiviral defense responses in tobacco and Nicotiana benthamiana, respectively. In addition, there were no drastic changes observed in the ratio of the two alternative transcripts during early tobamovirus infection. Our data suggest that Ntr may play a role as a negative regulator of N-dependent antiviral defenses.

Original languageEnglish
Pages (from-to)92-98
Number of pages7
JournalPhysiological and Molecular Plant Pathology
Volume84
Issue number1
DOIs
Publication statusPublished - 2013 Oct
Externally publishedYes

Fingerprint

Tobamovirus
hypersensitive response
Tobacco
Antiviral Agents
tobacco
Nicotiana benthamiana
alternative splicing
infection
Genes
genes
Alternative Splicing
Infection
elicitors

Keywords

  • Alternative splicing
  • Antiviral defense responses
  • Hypersensitive response
  • N resistance gene
  • Splice variant
  • Tobamovirus

ASJC Scopus subject areas

  • Genetics
  • Plant Science

Cite this

The splice variant Ntr encoded by the tobacco resistance gene N has arole for negative regulation of antiviral defense responses. / Sasaki, Nobumitsu; Takaoka, Masumi; Sasaki, Shobu; Hirai, Katsuyuki; Meshi, Tetsuo; Nyunoya, Hiroshi.

In: Physiological and Molecular Plant Pathology, Vol. 84, No. 1, 10.2013, p. 92-98.

Research output: Contribution to journalArticle

Sasaki, Nobumitsu ; Takaoka, Masumi ; Sasaki, Shobu ; Hirai, Katsuyuki ; Meshi, Tetsuo ; Nyunoya, Hiroshi. / The splice variant Ntr encoded by the tobacco resistance gene N has arole for negative regulation of antiviral defense responses. In: Physiological and Molecular Plant Pathology. 2013 ; Vol. 84, No. 1. pp. 92-98.
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