The structures of three new shishididemniols from a tunicate of the family Didemnidae

Hirotsugu Kobayashi, Yoshinari Miyata, Kohtaro Okada, Tsuyoshi Fujita, Takashi Iwashita, Yoichi Nakao, Nobuhiro Fusetani, Shigeki Matsunaga

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Three new serinolipid derivatives, shishididemniols C (1), D (2), and E (3), were isolated as antibacterial constituents of a tunicate of the family Didemnidae. Their planar structures were elucidated by interpretation of NMR and MS data, whereas the absolute stereochemistry was determined by chemical conversions. Shishididemniols C (3), D (4), and E (5) exhibited antibacterial activity against the fish pathogenic bacterium Vibrio anguillarum.

Original languageEnglish
Pages (from-to)6748-6754
Number of pages7
JournalTetrahedron
Volume63
Issue number29
DOIs
Publication statusPublished - 2007 Jul 16
Externally publishedYes

Keywords

  • Antibacterial
  • Serinolipid
  • Tunicate
  • Vibrio anguillarum

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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