Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Akihiko Kikuchi; Naokazu Idota; Jun Kobayashi; Teruo Okano

Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Akihiko Kikuchi^*, Naokazu Idota, Jun Kobayashi, Teruo Okano

^*Corresponding author for this work

Waseda Research Institute for Science and Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

Original language	English
Title of host publication	Polymer Preprints, Japan
Pages	5067-5068
Number of pages	2
Volume	55
Edition	2
Publication status	Published - 2006
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama Duration: 2006 Sept 20 → 2006 Sept 22

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
City	Toyama
Period	06/9/20 → 06/9/22

Keywords

Microfluidics
Nano-interfaces
Separation
Thermoresponse
Velving function

ASJC Scopus subject areas

Engineering(all)

Cite this

@inproceedings{c1fc34831efd459d94cf2be12a665361,

title = "Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules",

abstract = "We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.",

keywords = "Microfluidics, Nano-interfaces, Separation, Thermoresponse, Velving function",

author = "Akihiko Kikuchi and Naokazu Idota and Jun Kobayashi and Teruo Okano",

year = "2006",

language = "English",

volume = "55",

pages = "5067--5068",

booktitle = "Polymer Preprints, Japan",

edition = "2",

note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

}

TY - GEN

T1 - Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

AU - Kikuchi, Akihiko

AU - Idota, Naokazu

AU - Kobayashi, Jun

AU - Okano, Teruo

PY - 2006

Y1 - 2006

N2 - We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

AB - We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

KW - Microfluidics

KW - Nano-interfaces

KW - Separation

KW - Thermoresponse

KW - Velving function

UR - http://www.scopus.com/inward/record.url?scp=33846141532&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846141532&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:33846141532

VL - 55

SP - 5067

EP - 5068

BT - Polymer Preprints, Japan

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Abstract

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Keywords

ASJC Scopus subject areas

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