Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Akihiko Kikuchi, Naokazu Idota, Jun Kobayashi, Teruo Okano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

Original languageEnglish
Title of host publicationPolymer Preprints, Japan
Pages5067-5068
Number of pages2
Volume55
Edition2
Publication statusPublished - 2006
Event55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama
Duration: 2006 Sep 202006 Sep 22

Other

Other55th Society of Polymer Science Japan Symposium on Macromolecules
CityToyama
Period06/9/2006/9/22

Keywords

  • Microfluidics
  • Nano-interfaces
  • Separation
  • Thermoresponse
  • Velving function

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Kikuchi, A., Idota, N., Kobayashi, J., & Okano, T. (2006). Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules. In Polymer Preprints, Japan (2 ed., Vol. 55, pp. 5067-5068)