Three-dimensional analysis of small airway with X-ray micro-CT

Toshihiro Sera, Yuji Hasegawa, Robert C. Schroter, Kazuo Tanishita

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To identify the anatomy of small airways, we visualized and quantified the excised rat lung at varying lung volume using the microfocus X-ray CT. We insufflated tantalum dust as contrast agent. Lung volume was varied in steps from functional residual capacity (FRC: 2 mL) to the maximal lung capacity (MLC: 12 mL). At FRC we found out airway closure in small airways (Maximum lumen area was 0.06 mm 2 at MLC), where the bronchial walls are held in apposition. Lumen area dramatically varied at the first step during inflation and deflation, and the maximum area at MLC was 8 times as large as the minimum area at FRV.

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
EditorsR.D. Kamm, G.W. Schmid-Schoenbein, G.A. Atesian, M.S. Hefzy
Pages461-462
Number of pages2
Volume50
Publication statusPublished - 2001
Externally publishedYes
EventProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States
Duration: 2001 Jun 272001 Jul 1

Other

OtherProceedings of the 2001 Bioengineering Conference
CountryUnited States
CitySnowbird, UT
Period01/6/2701/7/1

Fingerprint

X rays
Tantalum
Dust
Rats

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Sera, T., Hasegawa, Y., Schroter, R. C., & Tanishita, K. (2001). Three-dimensional analysis of small airway with X-ray micro-CT. In R. D. Kamm, G. W. Schmid-Schoenbein, G. A. Atesian, & M. S. Hefzy (Eds.), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 50, pp. 461-462)

Three-dimensional analysis of small airway with X-ray micro-CT. / Sera, Toshihiro; Hasegawa, Yuji; Schroter, Robert C.; Tanishita, Kazuo.

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. ed. / R.D. Kamm; G.W. Schmid-Schoenbein; G.A. Atesian; M.S. Hefzy. Vol. 50 2001. p. 461-462.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Sera, T, Hasegawa, Y, Schroter, RC & Tanishita, K 2001, Three-dimensional analysis of small airway with X-ray micro-CT. in RD Kamm, GW Schmid-Schoenbein, GA Atesian & MS Hefzy (eds), American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. vol. 50, pp. 461-462, Proceedings of the 2001 Bioengineering Conference, Snowbird, UT, United States, 01/6/27.
Sera T, Hasegawa Y, Schroter RC, Tanishita K. Three-dimensional analysis of small airway with X-ray micro-CT. In Kamm RD, Schmid-Schoenbein GW, Atesian GA, Hefzy MS, editors, American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 50. 2001. p. 461-462
Sera, Toshihiro ; Hasegawa, Yuji ; Schroter, Robert C. ; Tanishita, Kazuo. / Three-dimensional analysis of small airway with X-ray micro-CT. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. editor / R.D. Kamm ; G.W. Schmid-Schoenbein ; G.A. Atesian ; M.S. Hefzy. Vol. 50 2001. pp. 461-462
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