Three more cyclotheonamides, C, D, and E, potent thrombin inhibitors from the marine sponge Theonella swinhoei

Youichi Nakao, Shigeki Matsunaga, Nobuhiro Fusetani

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Three new thrombin and trypsin inhibitors, cyclotheonamides C (3), D (4), and E (8) were isolated from the marine sponge Theonella swinhoei. Their structures were determined by spectral and chemical methods.

Original languageEnglish
Pages (from-to)1115-1122
Number of pages8
JournalBioorganic and Medicinal Chemistry
Volume3
Issue number8
DOIs
Publication statusPublished - 1995
Externally publishedYes

Fingerprint

Theonella
Trypsin Inhibitors
Porifera
Thrombin
cyclotheonamide D
cyclotheonamide E
cyclotheonamide C

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Molecular Biology
  • Molecular Medicine
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

Cite this

Three more cyclotheonamides, C, D, and E, potent thrombin inhibitors from the marine sponge Theonella swinhoei. / Nakao, Youichi; Matsunaga, Shigeki; Fusetani, Nobuhiro.

In: Bioorganic and Medicinal Chemistry, Vol. 3, No. 8, 1995, p. 1115-1122.

Research output: Contribution to journalArticle

@article{cd815acde40445849a6cf88d6278cbad,
title = "Three more cyclotheonamides, C, D, and E, potent thrombin inhibitors from the marine sponge Theonella swinhoei",
abstract = "Three new thrombin and trypsin inhibitors, cyclotheonamides C (3), D (4), and E (8) were isolated from the marine sponge Theonella swinhoei. Their structures were determined by spectral and chemical methods.",
author = "Youichi Nakao and Shigeki Matsunaga and Nobuhiro Fusetani",
year = "1995",
doi = "10.1016/0968-0896(95)00106-Q",
language = "English",
volume = "3",
pages = "1115--1122",
journal = "Bioorganic and Medicinal Chemistry",
issn = "0968-0896",
publisher = "Elsevier Limited",
number = "8",

}

TY - JOUR

T1 - Three more cyclotheonamides, C, D, and E, potent thrombin inhibitors from the marine sponge Theonella swinhoei

AU - Nakao, Youichi

AU - Matsunaga, Shigeki

AU - Fusetani, Nobuhiro

PY - 1995

Y1 - 1995

N2 - Three new thrombin and trypsin inhibitors, cyclotheonamides C (3), D (4), and E (8) were isolated from the marine sponge Theonella swinhoei. Their structures were determined by spectral and chemical methods.

AB - Three new thrombin and trypsin inhibitors, cyclotheonamides C (3), D (4), and E (8) were isolated from the marine sponge Theonella swinhoei. Their structures were determined by spectral and chemical methods.

UR - http://www.scopus.com/inward/record.url?scp=0029130165&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029130165&partnerID=8YFLogxK

U2 - 10.1016/0968-0896(95)00106-Q

DO - 10.1016/0968-0896(95)00106-Q

M3 - Article

VL - 3

SP - 1115

EP - 1122

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

SN - 0968-0896

IS - 8

ER -