Three more cyclotheonamides, C, D, and E, potent thrombin inhibitors from the marine sponge Theonella swinhoei

Youichi Nakao, Shigeki Matsunaga, Nobuhiro Fusetani

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Three new thrombin and trypsin inhibitors, cyclotheonamides C (3), D (4), and E (8) were isolated from the marine sponge Theonella swinhoei. Their structures were determined by spectral and chemical methods.

Original languageEnglish
Pages (from-to)1115-1122
Number of pages8
JournalBioorganic and Medicinal Chemistry
Volume3
Issue number8
DOIs
Publication statusPublished - 1995 Aug
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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