Three new bromotyrosine derivatives lethal to crab from the marine sponge, Pseudoceratina purpurea

Nobuhiro Fusetani; Yoshitsugu Masuda; Yoichi Nakao; Shigeki Matsunaga; Rob W.M. Van Soest

doi:10.1016/S0040-4020(01)00735-9

Three new bromotyrosine derivatives lethal to crab from the marine sponge, Pseudoceratina purpurea

Nobuhiro Fusetani, Yoshitsugu Masuda, Yoichi Nakao, Shigeki Matsunaga, Rob W.M. Van Soest

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Three new bromotyrosine-derived metabolites, tokaradines A (1), B (2), and C (3), were isolated from the marine sponge Pseudoceratina purpurea. Their structures were determined by spectral methods. Tokaradines were lethal to the crab Hemigrapsus sanguineus.

Original language	English
Pages (from-to)	7507-7511
Number of pages	5
Journal	Tetrahedron
Volume	57
Issue number	35
DOIs	https://doi.org/10.1016/S0040-4020(01)00735-9
Publication status	Published - 2001 Aug 27
Externally published	Yes

Keywords

Amine
Biologically active compounds
Pyridinium salt
Sponges

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Three new bromotyrosine derivatives lethal to crab from the marine sponge, Pseudoceratina purpurea",

abstract = "Three new bromotyrosine-derived metabolites, tokaradines A (1), B (2), and C (3), were isolated from the marine sponge Pseudoceratina purpurea. Their structures were determined by spectral methods. Tokaradines were lethal to the crab Hemigrapsus sanguineus.",

keywords = "Amine, Biologically active compounds, Pyridinium salt, Sponges",

author = "Nobuhiro Fusetani and Yoshitsugu Masuda and Yoichi Nakao and Shigeki Matsunaga and {Van Soest}, {Rob W.M.}",

note = "Funding Information: We thank Professor P. J. Scheuer of the University of Hawaii for editorial comments. This work was partly supported by a Grant-in-Aid from the Ministry of Education, Science, Culture and Sports of Japan.",

year = "2001",

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doi = "10.1016/S0040-4020(01)00735-9",

language = "English",

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T1 - Three new bromotyrosine derivatives lethal to crab from the marine sponge, Pseudoceratina purpurea

AU - Fusetani, Nobuhiro

AU - Masuda, Yoshitsugu

AU - Nakao, Yoichi

AU - Matsunaga, Shigeki

AU - Van Soest, Rob W.M.

N1 - Funding Information: We thank Professor P. J. Scheuer of the University of Hawaii for editorial comments. This work was partly supported by a Grant-in-Aid from the Ministry of Education, Science, Culture and Sports of Japan.

PY - 2001/8/27

Y1 - 2001/8/27

N2 - Three new bromotyrosine-derived metabolites, tokaradines A (1), B (2), and C (3), were isolated from the marine sponge Pseudoceratina purpurea. Their structures were determined by spectral methods. Tokaradines were lethal to the crab Hemigrapsus sanguineus.

AB - Three new bromotyrosine-derived metabolites, tokaradines A (1), B (2), and C (3), were isolated from the marine sponge Pseudoceratina purpurea. Their structures were determined by spectral methods. Tokaradines were lethal to the crab Hemigrapsus sanguineus.

KW - Amine

KW - Biologically active compounds

KW - Pyridinium salt

KW - Sponges

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JO - Tetrahedron

JF - Tetrahedron

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