Three new bromotyrosine derivatives lethal to crab from the marine sponge, Pseudoceratina purpurea

Nobuhiro Fusetani, Yoshitsugu Masuda, Yoichi Nakao, Shigeki Matsunaga, Rob W.M. Van Soest

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Three new bromotyrosine-derived metabolites, tokaradines A (1), B (2), and C (3), were isolated from the marine sponge Pseudoceratina purpurea. Their structures were determined by spectral methods. Tokaradines were lethal to the crab Hemigrapsus sanguineus.

Original languageEnglish
Pages (from-to)7507-7511
Number of pages5
JournalTetrahedron
Volume57
Issue number35
DOIs
Publication statusPublished - 2001 Aug 27
Externally publishedYes

Keywords

  • Amine
  • Biologically active compounds
  • Pyridinium salt
  • Sponges

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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