Time and position dependent surface flow velocity measurement in microfluidic devices

Yuzuru Iwasaki, Tsutomu Horiuchi, Takanobu Miwa, Shingo Nakamura, Michiko Seyama, Toru Miura, Suzuyo Inoue, Katsuyoshi Hayashi, Emi Tamechika, Shuji Hashimoto

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We have developed a simple method for measuring surface flow velocity inside a microfluidic channel. Tracking the refractive index boundary in the flow channel gave the flow velocity. The refractive index boundary was measured by surface plasmon resonance (SPR), thus our method gave both the physical flow condition and biological interaction information in a single sample run. In our previous attempt, we required the shape of the boundary to be predefined for tracking. In this report, we introduce a 2D Fourier transform based algorithm where no predefined shape is required for tracking, and we test its capability with a milk sample.

    Original languageEnglish
    Title of host publicationProceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
    PublisherChemical and Biological Microsystems Society
    Pages1891-1893
    Number of pages3
    ISBN (Print)9780979806452
    Publication statusPublished - 2012
    Event16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa
    Duration: 2012 Oct 282012 Nov 1

    Other

    Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
    CityOkinawa
    Period12/10/2812/11/1

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    Keywords

    • Flow velocity
    • Fourier transform
    • Refractive index
    • Surface plasmon resonance

    ASJC Scopus subject areas

    • Chemical Engineering (miscellaneous)
    • Bioengineering

    Cite this

    Iwasaki, Y., Horiuchi, T., Miwa, T., Nakamura, S., Seyama, M., Miura, T., Inoue, S., Hayashi, K., Tamechika, E., & Hashimoto, S. (2012). Time and position dependent surface flow velocity measurement in microfluidic devices. In Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 (pp. 1891-1893). Chemical and Biological Microsystems Society.