Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A

Seijiro Hosokawa, Masashi Seki, Hisato Fukuda, Kuniaki Tatsuta

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

(+)-Tubelactomicin A (1), an antitubercular lactone, has been synthesized from (S)-citronellol (2) and 2-deoxy-l-ribonolactone (18) through intramolecular Diels-Alder reaction, Suzuki-Miyaura coupling, and Shiina macrolactonization.

Original languageEnglish
Pages (from-to)2439-2442
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number14
DOIs
Publication statusPublished - 2006 Apr 3

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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