Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A

Seijiro Hosokawa, Masashi Seki, Hisato Fukuda, Kuniaki Tatsuta

    Research output: Contribution to journal › Article

    33 Citations (Scopus)

    Abstract

    (+)-Tubelactomicin A (1), an antitubercular lactone, has been synthesized from (S)-citronellol (2) and 2-deoxy-l-ribonolactone (18) through intramolecular Diels-Alder reaction, Suzuki-Miyaura coupling, and Shiina macrolactonization.

    Original languageEnglish
    Pages (from-to)2439-2442
    Number of pages4
    JournalTetrahedron Letters
    Volume47
    Issue number14
    DOIs
    Publication statusPublished - 2006 Apr 3

    Fingerprint

    Antitubercular Antibiotics
    Cycloaddition Reaction
    Lactones
    Anti-Bacterial Agents
    ribonolactone
    citronellol
    tubelactomicin A

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A. / Hosokawa, Seijiro; Seki, Masashi; Fukuda, Hisato; Tatsuta, Kuniaki.

    In: Tetrahedron Letters, Vol. 47, No. 14, 03.04.2006, p. 2439-2442.

    Research output: Contribution to journal › Article

    Hosokawa, S, Seki, M, Fukuda, H & Tatsuta, K 2006, 'Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A', Tetrahedron Letters, vol. 47, no. 14, pp. 2439-2442. https://doi.org/10.1016/j.tetlet.2006.01.140
    Hosokawa S, Seki M, Fukuda H, Tatsuta K. Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A. Tetrahedron Letters. 2006 Apr 3;47(14):2439-2442. https://doi.org/10.1016/j.tetlet.2006.01.140
    Hosokawa, Seijiro ; Seki, Masashi ; Fukuda, Hisato ; Tatsuta, Kuniaki. / Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A. In: Tetrahedron Letters. 2006 ; Vol. 47, No. 14. pp. 2439-2442.
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