Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A

Seijiro Hosokawa, Masashi Seki, Hisato Fukuda, Kuniaki Tatsuta

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    33 Citations (Scopus)

    Abstract

    (+)-Tubelactomicin A (1), an antitubercular lactone, has been synthesized from (S)-citronellol (2) and 2-deoxy-l-ribonolactone (18) through intramolecular Diels-Alder reaction, Suzuki-Miyaura coupling, and Shiina macrolactonization.

    Original languageEnglish
    Pages (from-to)2439-2442
    Number of pages4
    JournalTetrahedron Letters
    Volume47
    Issue number14
    DOIs
    Publication statusPublished - 2006 Apr 3

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    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

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