Abstract
(+)-Tubelactomicin A (1), an antitubercular lactone, has been synthesized from (S)-citronellol (2) and 2-deoxy-l-ribonolactone (18) through intramolecular Diels-Alder reaction, Suzuki-Miyaura coupling, and Shiina macrolactonization.
| Original language | English |
|---|---|
| Pages (from-to) | 2439-2442 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 47 |
| Issue number | 14 |
| DOIs | |
| Publication status | Published - 2006 Apr 3 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Cite this
Hosokawa, S., Seki, M., Fukuda, H., & Tatsuta, K. (2006). Total synthesis of an antitubercular lactone antibiotic, (+)-tubelactomicin A. Tetrahedron Letters, 47(14), 2439-2442. https://doi.org/10.1016/j.tetlet.2006.01.140