Total Synthesis of (‒)-Grayanotoxin III

Toshiyuki Kan, Seijiro Hosokawa, Shinji Nara, Masato Oikawa, Shinya Ito, Fuyuhiko Matsuda, Haruhisa Shirahama

Research output: Contribution to journalLetter

87 Citations (Scopus)


Total synthesis of (‒)-grayanotoxin III (3), a unique tetracyclic diterpene isolated from the leaves of various plants of the family Ericaceae, has been successfully accomplished featuring the highly stereoselective cyclization reactions induced by SmI2.

Original languageEnglish
Pages (from-to)5532-5534
Number of pages3
JournalJournal of Organic Chemistry
Issue number19
Publication statusPublished - 1994 Sep 1


ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Kan, T., Hosokawa, S., Nara, S., Oikawa, M., Ito, S., Matsuda, F., & Shirahama, H. (1994). Total Synthesis of (‒)-Grayanotoxin III. Journal of Organic Chemistry, 59(19), 5532-5534.