Total synthesis of palau'amine

Ian B. Seiple, Shun Su, Ian S. Young, Chad A. Lewis, Junichiro Yamaguchi, Phil S. Baran

Research output: Contribution to journalArticle

121 Citations (Scopus)

Abstract

(Figure Presented) Worth the wait: The long anticipated total synthesis of palau'amine has been accomplished by a route featuring highly chemoselective transformations, cascade reactions, and a remarkable transannular cyclization to secure the unprecedented trans-5,5 ring junction (shown in red).

Original languageEnglish
Pages (from-to)1095-1098
Number of pages4
JournalAngewandte Chemie - International Edition
Volume49
Issue number6
DOIs
Publication statusPublished - 2010 Feb 1
Externally publishedYes

Fingerprint

Cyclization
Amines
palau'amine

Keywords

  • Axinellamines
  • Massadine
  • Palau'amine
  • Total synthesis

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis

Cite this

Seiple, I. B., Su, S., Young, I. S., Lewis, C. A., Yamaguchi, J., & Baran, P. S. (2010). Total synthesis of palau'amine. Angewandte Chemie - International Edition, 49(6), 1095-1098. https://doi.org/10.1002/anie.200907112

Total synthesis of palau'amine. / Seiple, Ian B.; Su, Shun; Young, Ian S.; Lewis, Chad A.; Yamaguchi, Junichiro; Baran, Phil S.

In: Angewandte Chemie - International Edition, Vol. 49, No. 6, 01.02.2010, p. 1095-1098.

Research output: Contribution to journalArticle

Seiple, IB, Su, S, Young, IS, Lewis, CA, Yamaguchi, J & Baran, PS 2010, 'Total synthesis of palau'amine', Angewandte Chemie - International Edition, vol. 49, no. 6, pp. 1095-1098. https://doi.org/10.1002/anie.200907112
Seiple, Ian B. ; Su, Shun ; Young, Ian S. ; Lewis, Chad A. ; Yamaguchi, Junichiro ; Baran, Phil S. / Total synthesis of palau'amine. In: Angewandte Chemie - International Edition. 2010 ; Vol. 49, No. 6. pp. 1095-1098.
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