Total synthesis of selected bioactive natural products: Illustration of strategy and design

Kuniaki Tatsuta, Seijiro Hosokawa

Research output: Contribution to journalReview article

66 Citations (Scopus)


A review on the elegant parts and significance of the total synthesis of useful bioactive compounds is presented. Enumerated and discussed are the total syntheses of cochleamycin A, natural products possessing fused aromatic rings, nitrogen-containing polyhydroxy compounds and trichostatin D. The total synthesis using both glycosylation under mitsunobu conditions and stereoselective vinylogous mukaiyama aldol reaction are also discussed.

Original languageEnglish
Pages (from-to)4707-4729
Number of pages23
JournalChemical Reviews
Issue number12
Publication statusPublished - 2005 Dec 1


ASJC Scopus subject areas

  • Chemistry(all)

Cite this