Total synthesis, reactivity, and structural clarification of lindenatriene

James M. Eagan, Stephen Kyalo Kanyiva, Masahiro Hori, Scott A. Snyder

Research output: Contribution to journalArticle


The synthesis of lindenatriene (1) and iso-lindenatriene (12) were achieved, along with the des-hydroxy model compounds (10 and 18, respectively), and compared to reported 1 H NMR spectra in the literature (1a and 10a). These comparisons clarify the correct initial assignment of lindenatriene (1) as well as its instability and propensity to isomerize into the more thermodynamically favored iso-lindenatriene (12).

Original languageEnglish
Publication statusPublished - 2019 Jan 1
Externally publishedYes


  • Chloranthus
  • Dimer
  • Natural products
  • Sesquiterpene
  • Total synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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