Interpretive structural modelling (ISM) is a useful method employed in decision making in industrial and systems engineering fields. Moreover, ISM often plays an important role in structuralising particular issues or problems related to medical issues. A small number of elements can be straightforwardly calculated using ISM, but it is difficult to structuralise the problem with a large number of elements using electronic computers in polynomial time. In the real world, medical decision support systems (MDSS) are basically composed of electronic computer-based systems. Therefore, in this paper, we show results on the basis of using a bio-inspired ISM that measures the efficiency of combining a computer-based decision support system towards the creation of a new MDSS, using an example of a rehabilitation centre selection problem.