Toxadocial A: A novel thrombin inhibitor from the marine sponge Toxadocia cylindrica

Youichi Nakao; Shigeki Matsunaga; Nobuhiro Fusetani

doi:10.1016/S0040-4039(00)60332-5

Toxadocial A: A novel thrombin inhibitor from the marine sponge Toxadocia cylindrica

Youichi Nakao^*, Shigeki Matsunaga, Nobuhiro Fusetani

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

A unique thrombin inhibitor, named toxadocial A (1) has been isolated from the marine sponge Toxadocia cylindrica, and its structure was determined by spectroscopic and chemical methods to be a persulfated 7, 17, 31, 41-tetrahydroxyheptatetracontane-23-carbaldehyde.

Original language	English
Pages (from-to)	1511-1514
Number of pages	4
Journal	Tetrahedron Letters
Volume	34
Issue number	9
DOIs	https://doi.org/10.1016/S0040-4039(00)60332-5
Publication status	Published - 1993 Feb 26
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0040-4039(00)60332-5

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title = "Toxadocial A: A novel thrombin inhibitor from the marine sponge Toxadocia cylindrica",

abstract = "A unique thrombin inhibitor, named toxadocial A (1) has been isolated from the marine sponge Toxadocia cylindrica, and its structure was determined by spectroscopic and chemical methods to be a persulfated 7, 17, 31, 41-tetrahydroxyheptatetracontane-23-carbaldehyde.",

author = "Youichi Nakao and Shigeki Matsunaga and Nobuhiro Fusetani",

note = "Funding Information: Toxadocial A (1)7 contained sulfate groups which was inferred from an intense IB band at 1250 cm-l, as well as by a positive sodium rhodizonate test. 8 This was supported by a deshielded methine signal (6H 4.31 Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1993",

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day = "26",

doi = "10.1016/S0040-4039(00)60332-5",

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volume = "34",

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T2 - A novel thrombin inhibitor from the marine sponge Toxadocia cylindrica

AU - Nakao, Youichi

AU - Matsunaga, Shigeki

AU - Fusetani, Nobuhiro

N1 - Funding Information: Toxadocial A (1)7 contained sulfate groups which was inferred from an intense IB band at 1250 cm-l, as well as by a positive sodium rhodizonate test. 8 This was supported by a deshielded methine signal (6H 4.31 Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1993/2/26

Y1 - 1993/2/26

N2 - A unique thrombin inhibitor, named toxadocial A (1) has been isolated from the marine sponge Toxadocia cylindrica, and its structure was determined by spectroscopic and chemical methods to be a persulfated 7, 17, 31, 41-tetrahydroxyheptatetracontane-23-carbaldehyde.

AB - A unique thrombin inhibitor, named toxadocial A (1) has been isolated from the marine sponge Toxadocia cylindrica, and its structure was determined by spectroscopic and chemical methods to be a persulfated 7, 17, 31, 41-tetrahydroxyheptatetracontane-23-carbaldehyde.

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

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ER -

Toxadocial A: A novel thrombin inhibitor from the marine sponge Toxadocia cylindrica

Abstract

ASJC Scopus subject areas

UN SDGs

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