Trichopolyn VI: A new peptaibol insecticidal compound discovered using a recombinant Saccharomyces cerevisiae screening system

Takuya Suga; Yukihiro Asami; Shohei Hashimoto; Kenichi Nonaka; Masato Iwatsuki; Takuji Nakashima; Yoshihiro Watanabe; Ryohei Sugahara; Takahiro Shiotsuki; Takenori Yamamoto; Yasuo Shinohara; Naoya Ichimaru; Masatoshi Murai; Hideto Miyoshi; Satoshi Ōmura; Kazuro Shiomi

doi:10.2323/jgam.61.82

Trichopolyn VI: A new peptaibol insecticidal compound discovered using a recombinant Saccharomyces cerevisiae screening system

Takuya Suga, Yukihiro Asami, Shohei Hashimoto, Kenichi Nonaka, Masato Iwatsuki, Takuji Nakashima, Yoshihiro Watanabe, Ryohei Sugahara, Takahiro Shiotsuki, Takenori Yamamoto, Yasuo Shinohara, Naoya Ichimaru, Masatoshi Murai, Hideto Miyoshi, Satoshi Ōmura, Kazuro Shiomi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

In the course of searching for insecticides from soil microorganisms, we found that a fermentation broth of the fungus, Trichoderma brevicompactum FKI-6324, produced Trichopolyn VI, a new peptaibol, which possessed significant insecticidal potential. Spectroscopic analysis showed the compound to be a new trichopolyn I derivative. This paper describes the isolation, structure elucidation and biological activity of trichopolyn VI.

Original language	English
Pages (from-to)	82-87
Number of pages	6
Journal	Journal of General and Applied Microbiology
Volume	61
Issue number	3
DOIs	https://doi.org/10.2323/jgam.61.82
Publication status	Published - 2015 Jul 29
Externally published	Yes

Keywords

Insecticide
Peptaibol
Saccharomyces cerevisiae
Trichoderma brevicompactum
Trichopolyn

ASJC Scopus subject areas

Microbiology
Applied Microbiology and Biotechnology

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10.2323/jgam.61.82

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Suga, T., Asami, Y., Hashimoto, S., Nonaka, K., Iwatsuki, M., Nakashima, T., Watanabe, Y., Sugahara, R., Shiotsuki, T., Yamamoto, T., Shinohara, Y., Ichimaru, N., Murai, M., Miyoshi, H., Ōmura, S., & Shiomi, K. (2015). Trichopolyn VI: A new peptaibol insecticidal compound discovered using a recombinant Saccharomyces cerevisiae screening system. Journal of General and Applied Microbiology, 61(3), 82-87. https://doi.org/10.2323/jgam.61.82

Suga, T, Asami, Y, Hashimoto, S, Nonaka, K, Iwatsuki, M, Nakashima, T, Watanabe, Y, Sugahara, R, Shiotsuki, T, Yamamoto, T, Shinohara, Y, Ichimaru, N, Murai, M, Miyoshi, H, Ōmura, S & Shiomi, K 2015, 'Trichopolyn VI: A new peptaibol insecticidal compound discovered using a recombinant Saccharomyces cerevisiae screening system', Journal of General and Applied Microbiology, vol. 61, no. 3, pp. 82-87. https://doi.org/10.2323/jgam.61.82

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abstract = "In the course of searching for insecticides from soil microorganisms, we found that a fermentation broth of the fungus, Trichoderma brevicompactum FKI-6324, produced Trichopolyn VI, a new peptaibol, which possessed significant insecticidal potential. Spectroscopic analysis showed the compound to be a new trichopolyn I derivative. This paper describes the isolation, structure elucidation and biological activity of trichopolyn VI.",

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doi = "10.2323/jgam.61.82",

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AU - Suga, Takuya

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AU - Hashimoto, Shohei

AU - Nonaka, Kenichi

AU - Iwatsuki, Masato

AU - Nakashima, Takuji

AU - Watanabe, Yoshihiro

AU - Sugahara, Ryohei

AU - Shiotsuki, Takahiro

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AU - Ichimaru, Naoya

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AU - Ōmura, Satoshi

AU - Shiomi, Kazuro

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Trichopolyn VI: A new peptaibol insecticidal compound discovered using a recombinant Saccharomyces cerevisiae screening system

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Keywords

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