Trimethylphosphine-Promoted Alcoholysis of α,β-Unsaturated Imides and α,β-Unsaturated Esters

Haruka Sato, Seijiro Hosokawa

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    1 Citation (Scopus)

    Abstract

    α,β-Unsaturated imides and α,β-unsaturated esters were found to undergo alcoholysis in the presence of trimethylphosphine. The reaction is initiated by nucleophilic addition of trimethylphosphine to the double bond of the α,β-unsaturated carbonyl compound. Saturated imides also undergo the alcoholysis in the presence of the corresponding α,β-unsaturated imide.

    Original languageEnglish
    Pages (from-to)1343-1349
    Number of pages7
    JournalSynthesis (Germany)
    Volume50
    Issue number6
    DOIs
    Publication statusPublished - 2018 Mar 15

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    Keywords

    • alcoholysis
    • conjugate addition
    • transesterification
    • trimethylphosphine
    • unsaturated esters
    • unsaturated imides

    ASJC Scopus subject areas

    • Catalysis
    • Organic Chemistry

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