Abstract
Aim: Enhancement of lipoprotein lipase (LPL) activity through drug administration has been shown to increase pre-heparin serum LPL concentrations; however, pre-heparin serum LPL responses to exercise training have not been determined. The present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum LPL concentrations in overweight/obese men. Methods: Fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). All participants maintained ad libitum diets. Blood samples were collected at baseline and immediately after 12 weeks. The primary outcome was pre-heparin serum LPL. Results: Pre-heparin serum LPL concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean±SEM: 37.6±4.7 vs. 51.0±6.6 ng/mL, respectively, p=0.033). In the walking group, pre-heparin serum LPL concentrations remained unchanged after 12 weeks. Conclusions: This study demonstrates that 12 weeks of jogging training increases pre-heparin serum LPL concentrations in overweight/obese middle-aged men.
| Original language | English |
|---|---|
| Pages (from-to) | 21-29 |
| Number of pages | 9 |
| Journal | Journal of Atherosclerosis and Thrombosis |
| Volume | 17 |
| Issue number | 1 |
| Publication status | Published - 2010 |
| Externally published | Yes |
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Keywords
- Aerobic exercise
- Lipid metabolism
- Pre-heparin serum lipoprotein lipase
- Training
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Internal Medicine
- Biochemistry, medical
Cite this
Twelve-week jogging training increases pre-heparin serum lipoprotein lipase concentrations in overweight/obese middle-aged men. / Miyashita, Masashi; Eto, Miki; Sasai, Hiroyuki; Tsujimoto, Takehiko; Nomata, Yasuhiro; Tanaka, Kiyoji.
In: Journal of Atherosclerosis and Thrombosis, Vol. 17, No. 1, 2010, p. 21-29.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Twelve-week jogging training increases pre-heparin serum lipoprotein lipase concentrations in overweight/obese middle-aged men
AU - Miyashita, Masashi
AU - Eto, Miki
AU - Sasai, Hiroyuki
AU - Tsujimoto, Takehiko
AU - Nomata, Yasuhiro
AU - Tanaka, Kiyoji
PY - 2010
Y1 - 2010
N2 - Aim: Enhancement of lipoprotein lipase (LPL) activity through drug administration has been shown to increase pre-heparin serum LPL concentrations; however, pre-heparin serum LPL responses to exercise training have not been determined. The present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum LPL concentrations in overweight/obese men. Methods: Fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). All participants maintained ad libitum diets. Blood samples were collected at baseline and immediately after 12 weeks. The primary outcome was pre-heparin serum LPL. Results: Pre-heparin serum LPL concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean±SEM: 37.6±4.7 vs. 51.0±6.6 ng/mL, respectively, p=0.033). In the walking group, pre-heparin serum LPL concentrations remained unchanged after 12 weeks. Conclusions: This study demonstrates that 12 weeks of jogging training increases pre-heparin serum LPL concentrations in overweight/obese middle-aged men.
AB - Aim: Enhancement of lipoprotein lipase (LPL) activity through drug administration has been shown to increase pre-heparin serum LPL concentrations; however, pre-heparin serum LPL responses to exercise training have not been determined. The present study was undertaken to investigate the effects of 12 weeks of supervised aerobic exercise training on pre-heparin serum LPL concentrations in overweight/obese men. Methods: Fifteen overweight/obese middle-aged men were assigned to one of two 12-week supervised exercise interventions: a walking group (eight participants gradually increasing brisk walking to 60 min/day 3 days a week) or a jogging group (seven participants gradually increasing jogging to 60 min/day 3 days a week). All participants maintained ad libitum diets. Blood samples were collected at baseline and immediately after 12 weeks. The primary outcome was pre-heparin serum LPL. Results: Pre-heparin serum LPL concentrations were increased in the jogging group after 12 weeks compared with the baseline values (mean±SEM: 37.6±4.7 vs. 51.0±6.6 ng/mL, respectively, p=0.033). In the walking group, pre-heparin serum LPL concentrations remained unchanged after 12 weeks. Conclusions: This study demonstrates that 12 weeks of jogging training increases pre-heparin serum LPL concentrations in overweight/obese middle-aged men.
KW - Aerobic exercise
KW - Lipid metabolism
KW - Pre-heparin serum lipoprotein lipase
KW - Training
UR - http://www.scopus.com/inward/record.url?scp=76249099916&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=76249099916&partnerID=8YFLogxK
M3 - Article
C2 - 20075597
AN - SCOPUS:76249099916
VL - 17
SP - 21
EP - 29
JO - Journal of Atherosclerosis and Thrombosis
JF - Journal of Atherosclerosis and Thrombosis
SN - 1340-3478
IS - 1
ER -