Ultrasensitive detection of biomolecules using functionalized multi-walled carbon nanotubes

PingAn Hu, Takashi Tanii, Guo Jun Zhang, Takumi Hosaka, Iwao Ohdomari

    Research output: Contribution to journalArticle

    19 Citations (Scopus)

    Abstract

    An ultrasensitive and facile bioassay approach is developed using biofunctional multi-walled carbon nanotubes (MWNTs). The biofunctional MWNTs are exploited to detect trace protein in the homogeneous solution using fluorescent detection. The effect of target concentration on the fluorescent intensity is systematically studied, revealing that the detected signal is strengthened with increase in target concentration. The homogenous target-capture process performed on the biofunctional MWNTs enhances the detection sensitivity largely. The detection limit of 100 pg/ml is achieved through this bioassay.

    Original languageEnglish
    Pages (from-to)161-166
    Number of pages6
    JournalSensors and Actuators, B: Chemical
    Volume124
    Issue number1
    DOIs
    Publication statusPublished - 2007 Jun 10

    Fingerprint

    Carbon Nanotubes
    Biomolecules
    Carbon nanotubes
    bioassay
    Bioassay
    carbon nanotubes
    proteins
    Proteins

    Keywords

    • Biomolecules
    • Carbon nanotubes
    • Detection

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Electrochemistry
    • Electrical and Electronic Engineering

    Cite this

    Ultrasensitive detection of biomolecules using functionalized multi-walled carbon nanotubes. / Hu, PingAn; Tanii, Takashi; Zhang, Guo Jun; Hosaka, Takumi; Ohdomari, Iwao.

    In: Sensors and Actuators, B: Chemical, Vol. 124, No. 1, 10.06.2007, p. 161-166.

    Research output: Contribution to journalArticle

    Hu, PingAn ; Tanii, Takashi ; Zhang, Guo Jun ; Hosaka, Takumi ; Ohdomari, Iwao. / Ultrasensitive detection of biomolecules using functionalized multi-walled carbon nanotubes. In: Sensors and Actuators, B: Chemical. 2007 ; Vol. 124, No. 1. pp. 161-166.
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