@article{f0263978ac5c4d10b3001cead4591bf4,
title = "Unified synthesis of multiply arylated alkanes by catalytic deoxygenative transformation of diarylketones",
abstract = "A deoxygenative transformation of diarylketones leading to multiply arylated alkanes was developed. Diarylketones were reacted with diphenylphosphine oxide resulting in a phospha-Brook rearrangement, followed by palladium-catalyzed cross-couplings or a Friedel-Crafts type alkylation to afford the corresponding multiply arylated alkanes. A variety of diarylketones can be converted to multiply arylated alkanes such as diarylmethanes, tetraarylethanes, and triarylmethanes by reduction, dimerization, and arylation in one pot. Furthermore, a one-pot conversion from arylcarboxylic acids to diarylmethanes and tetraarylethanes, and a synthesis of tetraarylmethane and triphenylethane using sequential coupling reactions are also presented.",
author = "Kurosawa, {Miki B.} and Kenta Kato and Kei Muto and Junichiro Yamaguchi",
note = "Funding Information: This work was supported by JSPS KAKENHI Grant Number JP21K18966, JP21H05213 (to J.Y.), and JP21K05079 (to K.M.). This work was also partly supported by JST ERATO Grant Number JPMJER1901 (to J.Y.). We thank Mizuho Watanabe to help a part of experiment. We also thank Iwatani Corporation for providing CsCO as a gift. The Materials Characterization Central Laboratory in Waseda University is acknowledged for the support of HRMS measurement. We also would like to thank National Institute of Health Sciences in Japan for the support of NMR measurement. 2 3 Funding Information: This work was supported by JSPS KAKENHI Grant Number JP21K18966, JP21H05213 (to J.Y.), and JP21K05079 (to K.M.). This work was also partly supported by JST ERATO Grant Number JPMJER1901 (to J.Y.). We thank Mizuho Watanabe to help a part of experiment. We also thank Iwatani Corporation for providing Cs2CO3 as a gift. The Materials Characterization Central Laboratory in Waseda University is acknowledged for the support of HRMS measurement. We also would like to thank National Institute of Health Sciences in Japan for the support of NMR measurement. Publisher Copyright: {\textcopyright} 2022 The Royal Society of Chemistry.",
year = "2022",
month = aug,
day = "22",
doi = "10.1039/d2sc03720c",
language = "English",
volume = "13",
pages = "10743--10751",
journal = "Chemical Science",
issn = "2041-6520",
publisher = "Royal Society of Chemistry",
number = "36",
}