Unprecedentedly fast DNA hydrolysis by the synergism of the cerium(IV)-praseodymium(III) and the cerium(IV)-neodymium(III) combinations

Naoya Takeda, Takamitsu Imai, Makoto Irisawa, Jun Sumaoka, Mono Yashiro, Hidemi Shigekawa, Makoto Komiyama

Research output: Contribution to journalArticle

24 Citations (Scopus)


The most active catalysts for DNA hydrolysis so far have been obtained by using the synergetic cooperation of the cerium(IV) ion with the praseodymium(III) ion. The pseudo first-order rate constant for the hydrolysis of thymidylyl(3'-5')thymidine by the 2:1 combination is 10 times as great as that by the cerium(IV) ion.

Original languageEnglish
Pages (from-to)599-600
Number of pages2
JournalChemistry Letters
Issue number8
Publication statusPublished - 1996
Externally publishedYes


ASJC Scopus subject areas

  • Chemistry(all)

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